RESEARCH PLAN

Principal Investigator/Program Director Williams, Robert W.

• Problems and Issues Addressed.

• Aim 1. Extend the MBL.

• Aim 2. Generate a Relational database for the MBL.

• Aim 3. Enhance the Interface.

• Aim 4. Create Image Analysis Tools.

• Status of Current Research Efforts.

• Mapping Quantitative Trait Loci.

• Stereology and Neuroscience.

• QTLs for CNS Morphometric Traits.

• Measuring Brain Weight.

• Selectivity of QTLs.

• Mapping Brain Weight QTLs.

• QTLs for Retinal Ganglion Cells.

• Gross Morphologic Measures.

• The Mouse Brain Library.

• Bioinformatics Components of the current Mouse Brain Library.

• Limitations of Existing Approaches.
  

EXPERIMENTAL PLAN

• 1. Extend the MBL.
• 2. Changes to the Underlying Data Structure.
• 3. Changes to the Interface.
• 4. Image Analysis.
• Time Line.