Lu Lu
EDUCATION
1999-2001: |
Ph.D. (1983) Physiology, University
of California, Davis
B.A. (1975) Psychobiology, University
of California, Santa Cruz
|
INTERESTS
|
• Mammalian neurogenetics
• Complex trait analysis and functional
genomics • Visual system development
and function and genetics of myopia
• Control of cell proliferation
and cell death in the CNS |
PROFESSIONAL EXPERIENCE
2001–present |
William and Dorothy Dunavant Chair of
Excellence in Developmental Genetics:
Department of Pediatrics (2nd appointment),
University of Tennessee |
2000–present |
Codirector: Center of Genomics and Bioinformatics,
University of Tennessee |
2001–present |
Member: Feinstone Center for Genomic Research,
University of Memphis |
1997–present |
Professor: Department of Anatomy and
Neurobiology and Center for Neuroscience,
University of Tennessee Health Science
Center (primary) |
2001–present |
Professor: Department of Pediatrics |
1992–1997 |
Associate Professor: Department of Anatomy
and Neurobiology and Center for Neuroscience,
University of Tennessee |
1989–1992 |
Assistant Professor: Department of Anatomy
and Neurobiology and Center for Neuroscience,
University of Tennessee |
1986–1989 |
Assistant Professor: Yale University
School of Medicine, Section of Neuroanatomy |
1985–1986 |
Associate Research Scientist: Yale University
School of Medicine, Section of Neuroanatomy
(P. Rakic, mentor) |
1984–1989 |
Instructor, Neuroanatomy laboratory:
Yale University School of Medicine, Section
of Neuroanatomy |
1983–1985 |
Postdoctoral fellow: Yale University
School of Medicine, Section of Neuroanatomy,
(P. Rakic, mentor) |
1982–1983 |
Assistant Research Physiologist: University
of California, Davis |
1982 |
Instructor: University of California,
Davis |
1979–1982 |
National Institutes of Health Trainee:
University of California, Davis, (L.M.
Chalupa, thesis advisor) |
1978–1981 |
Teaching Assistant and Teaching Associate:
Animal Physiology and Psychology, University
of California, Davis |
Professional SOCIETIES
|
President-elect: International Behavioural and Neural Genetics Society (2004–2005) |
|
Society for Neuroscience |
|
American Society of Human Genetics |
|
Association for Research in Vision and Ophthalmology |
|
Society for the Study of Evolutionary Biology |
|
International Mammalian Genome Society |
|
Society for Developmental Biology |
|
International Behavioural and Neural Genetics Society |
|
Behavior Genetics Association |
Grants and Fellowships
2001–present |
Principal Investigator: National Institutes
of Health. “INIA: Complex Trait Analysis
of Alcohol-Stress Interactions” U01AA13499.
TDC approx. $1.68M over 5 years (02.01.02–12.31.06). |
2001–present |
Principal Investigator: National Institutes
of Health. “INIA: Genotyping Core”
1U24AA13513. TDC approx. $600,000 over 5 years
(01.01.02–12.30.06). |
2000–present |
Principal Investigator: National Institutes
of Health and National Science Foundation, Human
Brain Project. “Informatics Center for
Mouse Neurogenetics” P20-MH62009
and IBN-0003982. TDC approx. $5.4 million over
5 years (7.1.00–6.30.05, 32%). |
2000–present |
Principal Investigator: National Institutes
of Health. “Genetic and Epigenetic Control
of Eye Growth” R01 EY12991. TDC
$200,00 year 1, $800,000 all years (9.1.00–7.31.04,
30%). |
1999–2002 |
Principal Investigator: National Institutes
of Health. “Biometric and Functional Studies
of the Eye and Retina” R01 EY13070. TDC
$150,000 year 1, $444,381 all years (12.01.99–11.30.02
25%). |
2001 |
Principal Investigator: NIHLB Mammalian Genotyping
Service. "High Resolution QTL Mapping in
Mice" (7.1.01). Grant funds 350,000 genotypes. |
2001 |
Collaborator: National Institutes of Health.
"Sleep Patterns During Infectious Disease"
NL70522. TDC $225,00 year 1, $1.11M all years
(9.19.01–7.31.05; PI Linda Toth, no funded
effort). |
2000–present |
Eye Domain coinvestigator: National Institutes
of Health. “Targeted Mutagenesis of the
Mouse Genome and Neural Phenotypes” U01-MH61971,
TDC, $2,664,000/year (D. Goldowitz, PI, M. Jablonski,
domain PI) (funding from 7.1.00–6.30.05,
RW 5%). |
2000 |
Principal Investigator: NIHLB Mammalian Genotyping
Service. "An Advanced Intercross for Mapping
Multigenic Morphometric Traits in Mice: A Community
QTL Mapping Resource" (1.1.00). Grant funded
~190,000 genotypes. |
1996–2000 |
Principal Investigator: National Institutes
of Health. “Genetic Control of Neuron
Populations” R01 NS35485. TDC ~$733,000
all years (07.1.96 to 07.31.00, 20%). |
1987–2000 |
Principal Investigator: National Institutes
of Health. “Growth of Optic Nerve Fibers”
R01 EY06627-10. TDC, $437,500 (12.1.95 to 05.30.00). |
1991–1994 |
Principal Investigator: National Institutes
of Health. “Development and Clonal Structure
of the Mammalian Retina” R01 EY 08868–03.
TDC, $260,518 |
1992–1996 |
Co-Principal Investigator: National Institutes
of Health. “Genetic Basis of Retinal Development”
R01 EY09586-03. P.I, Dan Goldowitz, TDC, $505,991
(4.1.92 to 3.31.96). |
Awards
|
Loren D. Carlson Prize in Physiology, 1982-83 |
|
Fellow Award, Winter Conference on Brain Research, 1987 |
|
Excellence in Teaching Award, 1995 |
Patents
|
Tissue Analyzer: Inventors Robert W. Williams,
Pasko Rakic, U.S. Patent 4,932,044; filed November
4, 1988; issued June 5, 1990. See http://www.patents.ibm.com/claims?patent_number=4932044 |
|
Method for ultra-high resolution mapping of
genes and determination of genetic networks
among genes underlying phenotypic traits: Inventors
David W. Threadgill (Chapel Hill NC) and Robert
W. Williams (Memphis TN), U.S. Patent Application
(Preliminary) filed December 1, 2000. |
|
Method for determining sensitivity to environmental
toxins and susceptibility to Parkinson’s
disease. Inventors: Richard Smeyne (Memphis
TN) and Robert W. Williams (Memphis TN). U.S.
Patent Application (Preliminary), to be filed. |
Symposia, Conferences, Committees
2004 |
co-organizer, 3rd Annual Complex Trait Consortium
meeting, Bar Habor, July 6–9 |
2004 |
Organizer, 10th International Summer School
on Behavioral Neurogenetics (Memphis TN, August
8–15 |
2003 |
Mouse Atlas Workshop (NIMH Office of Neuroinformatics),
Nov 18, 2003 |
2003 |
Behavior Genetics Association Symposium: Chicago
June 27 |
2003 |
Mouse Initiatives V: Genomics of Complex System
in Biomedical Research, July 31–Aug 2,
www.jax.org/courses/mi5_03.html |
2003 |
Joint Statistics Meeting symposium speaker:
San Francisco, Aug 4 to 6. |
2003 |
Society for Neuroscience Brain Information Group
member |
2003 |
Keynote: 9th International Summer School on
Behavioral Neurogenetics, Aug 6–9. Toulouse,
France |
2002 |
National Cancer Institute: Mouse Models of Human
Cancers Consortium- Roundtable, Newport Beach
CA, Dec 11–13. |
2002 |
Lecturer: NIDA Addiction Studies Workshop for
Journalist (Tuscon AZ, Dec 8) |
2003 |
Spring Brain Conference Plenary Session organizer:
Identifying Genes Controlling Brain Structure
and Behavior using Complex Trait Analysis, Sedona,
March 12–15 |
2002 |
Chair: Bioinformatics 2002, Society for
Neuroscience Short Course, Orlando FL, Nov 2 |
2002 |
Instructor: 8th International Summer School
on Behavioral Neurogenetics, Aug 5–9.
Worcester MA. |
2001 |
Chair: International Complex Trait Consortium,
Edinburgh, Oct.23, 2001 and Memphis, May2. |
2001 |
Sponsor and organizing committee: 4th Annual
Meeting: International Behavioral and Neural
Genetics Society, San Diego, Nov. 8–9 |
2001 |
Workshop presentation: South-East Regional Meeting
of the Society of Developmental Biology, Montreat
NC, May 24 |
2001 |
Invited speaker: Neuroinformatics Faces Functional
Genomics symposium: Natcher Building: Bethesda
MD, May 22: Tools for Collaborative Analysis
of Complex Neurodevelopmental and Behavioral
Traits. |
2000 |
Invited speaker: NIAAA-sponsored QTL meeting:
Washington DC (Dec 1; organized by Robert Karp) |
2000 |
Invited participant: Human Brain Project: Neuroinformatics
Satellite Symposium. New Orleans (Nov 4,; presentation
by GD Rosen) |
1999 |
Co-organizer: Symposium on QTL Mapping, Behavior
Genetics Association, Vancouver, Canada, July |
1999 |
Co-organizer and sponsor: The Molecular Biology/Molecular
Genetics of the Visual System, Center for Vision
Research Memphis TN (Mar 26) |
1999 |
Participant: Gordon Research Conference in Quantitative
Genetics. Ventura, CA (Feb 14–19) |
1998 |
Course Lecturer: Short Course in Quantitative
Neuroanatomy. Society for Neuroscience, Los
Angeles CA |
1998 |
Chairman: American Association of Anatomists:
Experimental Biology 98: Experimental Biology:
Symposium on Quantitative Neurobiology and the
Human Brain Project |
1996 |
Chairman: Mouse Chromosome 7 Committee: International
Mammalian Genome Society |
1998 |
Presentation: Chautauqua Short Course for college
teachers in neuroscience |
1997 |
Chairman: American Association of Anatomists:
Experimental Biology 97: Mini-symposium on Quantitative
Neurobiology |
1994 |
Co-chairman: Mouse Chromosome 7 Committee: International
Mammalian Genome Society (1994–1996) |
1989 |
Organizer: Winter Brain Conference Workshop,
“Different Strategies of Brain Development,”
Co-organized with Karl Herrup. Jan. 1989 |
1996 |
Co-organizer: Symposium on Cortical Development,
Center for Neuroscience, University of Tennessee,
June 1996 |
1991 |
Participant: The Jackson Laboratory, “Short
Course in Medical and Experimental Mammalian
Genetics ” Aug. 1991 |
1985 |
Participant: Gordon Research Conference, “Central
Nervous System,” Tilton School, New Hampshire,
June 1985 |
1983 |
Participant: The Neuroscience Institute, “Molecular
Bases of Neuronal Development,” The Salk
Institute, October 1983 |
1981 |
Participant: NATO Advanced Studies Institute,
“Formation of Neuronal Connections,”
Varenna, Italy, May 1981 |
Visiting Scientist
2000–2002 |
Advisory Professor, Fudan University, Shanghai |
2000–present |
Collaborator, with Profs Tan and Gu, Nantong
Medical College, |
1997 |
Harvard University, Beth Israel Hospital, Dr.
Glenn Rosen, June 1997 |
1996 |
The California Institute of Technology, Drs.
John Allman and Scott Fraser, Aug. 1996 |
1993 |
The Jackson Laboratory, Dr. Muriel Davisson,
July 1993 |
Scientific Advisory Boards
2003–2005 |
Portland Alcohol Research Center, VAMC Portland |
2001–2003 |
Genome Explorations Inc. |
Invited Seminars and Lectures (Incomplete List)
|
MGH Harvard: Feb 25, 2004 |
|
Washington University: |
|
Yale University, Department of Genetics, Dec 16, 2003 |
|
University of Chicago, Committee on Genetics, Dec. 2, 2003 |
|
American Society of Human Genetics symposium speaker: Nov 5, 2003 |
|
Vanderbilt University, Neuroscience: Oct 22, 2003 |
|
Nathan Kline Institute: Oct 17, 2003 |
|
Oregon Health Science symposium, Oct 9, 2003 |
|
Special lecture: 9th international summer school on behavioral neurogenetics, Toulouse, Aug 5, 2003. |
|
Symposium at the Joint Statistics Meeting,,Aug 3, 2003, San Francisco |
|
Mouse Initiatives V meeting, Jackson Laboratory, Aug 1, 2003 |
|
Symposium at Behavioral Genetics Association, June 26, 2003, Chicago |
|
Purdue University: June 19, 2003 |
|
Human Brain Project, Bethesda: May 12, 2003 Natcher Center presentation: http://videocast.nih.gov/ram/brain051203.ram |
|
Pennsylvania State University: May 2, 3, 2003: Genomics Spring Fever: Complex Genetics of Brain and Behavior |
|
St Jude Children�s Research Hospital, Feb 6, 2003: Dissecting Transcriptional Networks (Affy Memphis User Group Meeting) |
|
University of Toronto, Mt. Sinai Hospital, Feb 4, 2003 |
|
University of T�bingen: Neurobiology of Vision, July 9�10, 2002 |
|
Wake Forrest University, Drug Addiction Workshop for Journalist, Dec 2002 (Tucson AZ) |
|
Wadsworth Center, Albany New York, Feb 2003 |
|
University of California, Davis, Dec 2002 |
|
University of Memphis, Sept 13, 2002 |
|
Wilmer Eye Institute, Johns Hopkins University, Aug 29, 2002. The Complex Genetics of Eye and Brain Development: Gene Network Analysis using Microarrays |
|
King�s College, London: July 7, 2002 |
|
University of Alabama, Section of Statistical Genetics, June 17, 2002 |
|
New England College of Optometry, Apr 25, 2002 |
|
University of Tennessee Health Science Center, Grand Rounds in Pediatrics, Mar 13, 2002 |
|
Southern Illinois University, School of Medicine, Mar 15, 2002 |
|
Neuroinformatics. The 35th Annual Winter Conference on Brain Research, Jan.27, 2002 |
|
New Mouse Behavioral Phenotyping Assays: Half Moon Bay CA, Dec 2001 |
|
Society for Developmental Biology, Southeast Regional Meeting, Workshop presentation, May 2001 |
|
Human Brain Project Conference, Natcher Center, NIH, May 2001 |
|
Cornell University, Department of Psychology and Dept of Neuroscience, Apr 2001 |
|
Stanford University, Apr 12, 2001 |
|
University of Alabama, Birmingham, Department of Medicine, Mar 21, 2001 |
|
MCP-Hahneman, Department of Neuroscience, Mar 14, 2001 |
|
UCLA, Neuroscience Grand Rounds, Feb 7, 2001 |
|
Shanghai Medical University (Fudan), Department of Histology and Embryology, Nov 2000 |
|
Beijing Medical University, Department of Histology and Embryology, Nov 2000 |
|
Nantong Medical College, Neuroscience Institute, Nov 2000 |
|
University of North Carolina, Chapel Hill, Department of Genetics, Oct 23, 2000 |
|
University of Tennessee, Biomedical Engineering Joint Program, Sept 14, 2000 |
|
Cold Spring Harbor, Banbury Center, August 28, 2000 |
|
University of California, Santa Barbara, Neuroscience Research Institute, May 26, 2000. Quantitative Genetics of CNS development: View from the trailhead |
|
State University of New York at Buffalo, Roswell Park Cancer Institute, May 8, 2000 |
|
Drexel University, Department of Biomedical Engineering, Nov 2, 1999 |
|
University of Michigan, Department of Genetics, Oct 5, 1999 |
|
Vanderbilt University, Vision Research Center, May 7, 1999. The genetics of brain evolution |
|
University of California, Santa Barbara, Neuroscience Research Institute, Feb 16, 1999 |
|
Case Western Reserve University, Department of Neurosciences, Cleveland OH, Jan 21, 1999 |
|
VA Medical Center, Memphis TN, Nov 20, 1998 (New Power of Forward Genetics: Analysis of Polygenic Traits that Control Disease and Development) |
|
Case Western Reserve University, Depts Ophthalmology and Genetics, Cleveland OH, Nov 18, 1998 |
|
Yale University, Department of Neuroanatomy, New Haven CT, July 1998 |
|
University of Southern California, Department of Anatomy & Neuro, June 1998 |
|
University of California, San Diego, Department of Neuroscience, June 1998 |
|
Mount Sinai Medical School, Department of Neuroscience, New York, NY, June 1997 |
|
Harvard University, Beth Israel Deaconess, Department of Neurology, June 1997 |
|
Pasteur Institute, Paris, France. Oct. 1996 |
|
Conference on Brain Evolution, Ithaca, NY, June 1995 |
|
California Institute of Technology, Pasadena, CA. Nov. 1995 |
|
National Cancer Institute (Steve O'Brien) Frederick, MD, June 9, 1994 |
|
The Jackson Lab Bioinformatics Group, Bar Harbor Maine, July 1993 |
|
25th Annual Meeting of the Biomedical Engineering Society, Memphis, Oct. 24, 1993 |
|
University of Utah, Department of Biology, Salt Lake City, UT, Jan. 1989 |
|
Winter Conference for Brain Research, Snowbird, Utah, Jan. 1989 |
|
University of Texas, Houston, Department of Neurobiology and Anatomy, Dec 1988 |
|
SUNY, Stony Brook, Department of Neurobiology, Oct 1988 |
|
Winter Conference for Brain Research, Vail, Colorado, Jan. 1987 |
|
Conference on the Development of the Vertebrate Retina, Ithaca, N.Y., June 1987 |
|
New York University, Department of Physiology and Neuroscience, Oct 1986 |
|
University of Rochester, Center for Visual Sciences, Rochester, N.Y., Apr 1986 |
|
Rush-Presbyterian-St. Luke's Medical Center, Chicago, Nov 1986 |
|
University of California, Davis, Department of Psychology, June 1985 |
|
Stanford University, Department of Neurobiology, June 1985 |
|
SUNY, Albany, N.Y., Department of Biological Sciences, Jan 1984 |
REVIEWER FOR
|
Anatomy
and Embryology, Behavior Genetics, Brain Behavior
and Evolution, Behavioral Brain Sciences, Cerebral
Cortex, Current Biology, Developmental Biology,
European Journal of Neuroscience, Experimental
Eye Research, Gene Expression Patterns, Genesis,
Genomics, Investigative Ophthalmology and Vision
Science, Journal of Comparative Neurology, Journal
of Heredity, Journal of Neurobiology, Journal
of Neurochemistry, Journal of Neurophysiology,
Journal of Neuroscience, Journal of Neuroscience
Methods, Molecular Vision, Nature Genetics,
Neuroscience, Optometry and Vision Research,
Proceedings of the National Academy of Science,
Science, Visual Neuroscience, Vision Research |
EDITORIAL BOARDS/COMMITEES
2003–2006 |
Society for Neuroscience: Committee on Animals
in Research |
2002–present |
Gene, Brain and Behavior: board member |
2002–present |
Neuroinformatics: board member |
2002 |
Gene Expression Patterns: board member |
2001–present |
BioMed Central Neuroscience: core reviewer
board member www.biomedcentral.com/info/biologyeditorial.asp |
2001–present |
Behavior Genetics: board member |
2000 |
Behavior Genetics: guest editor |
1995–present |
Molecular Vision: board member |
1993–present |
European Journal of Anatomy: board member |
GRANT PROPOSAL REVIEWS
2004 |
21st Century Fund Review (State of Indiana) |
2004 |
Chair NIH ZRG1 IDM-K (04) Host Genetics of Viral
Pathogenesis Mar 15, 2004 |
2004 |
Chair NIH MDCN-G (55) Human Brain Project, Feb
6, 7, 2004 |
2003 |
MRC Program Review (July 2003) |
2002 |
BISTI SS-E(51) and Human Brain Project SS-E(95),
Oct 22–25, 2002 |
2002 |
MCDN Special Review panel ZRG1 SSS-P 09 S (Sept
6, 2002) |
2002 |
NEI Special Review panel ZEY1 VSN 06 R (Aug
2002) |
2002 |
Science Foundation Ireland reviewer (July 2002) |
2002 |
NIH Mammalian Genetics IRG (June 2002) |
2002-2003 |
Mammalian Genotyping Advisory Panel (Apr 2002,
2003) |
2002 |
NIH Special Review (Feb 8, 2002) |
2001 |
NIH Innovations in Biomedical Science Tech ZRG1
SSS-7 21 B (Nov 6, 2001) |
2001 |
NIH BISTI Panel Reviewer ZRG1 SSS-E01 1 (July
2001, Nov 2001) |
2001 |
NIH CSR Reviewer ZRG1FCN-3 01 BISTI (July 19,
2001) |
2001 |
NIH Special Emphasis Panel ZRG1 SSS-R (02) (July
2, 2001) |
2001 |
NIEHS Review Panel (Inbred Rodents) ES-01-05
(June 29, 2001) |
2001 |
Medical Research Council (UK) Strategic Grants
Reviewer |
2000 |
Fonds voor Weterschappelijk Onderzoek - Vlaanderen
(Belgian NIH) |
2000 |
NIH VISB Study Section Ad Hoc Member (6/00) |
2000 |
NIMH Special Emphasis Panel Reviewer (Gene Array
RFA MH-00-002, 7/00) |
2000 |
UT System-wide Advisory Panel: Biotechnology
and Biological Sciences Review (7/00) |
1999 |
NIH VISC Study Section Ad Hoc Member (2/99) |
1999 |
NIMH Center Grant Reviewer |
1999 |
NIMH Special Emphasis Panel Reviewer ZMH1 BRB-I |
1998 |
Department of Veterans Affairs: Merit Review
Consultant |
1995 |
Consultant to NIH VIS-B Study Section |
Teaching
2001–present |
Course co-director: Neuroscience Seminar Series
(NS8XX): a graduate level course, 15–20
contact hours, ~15 students/year. |
1992–present |
Course director: Morphological Neuroscience
(NS822): a graduate level course, ~40 contact
hours, ~ 8 students/year. |
2003–present |
Lecturer: Comparative Medicine CM712, UTHSC:
Mouse Genetics (graduate level) |
2003–present |
Lecturer: Bioinformatics, University of Memphis
(graduate level) |
2000–2002 |
Lecturer and Lab: Medical Neuroanatomy (M):
~20 contact hours, Lectures in CNS development.
150 students/year. |
2002–2003 |
Short Course director: Society of Neuroscience,
Bioinformatics |
2003 |
Course co-director: Memphis Microarray Short
Course (June 4 to June 12, 2003) |
2002 |
Lecturer: NIDA Addiction Studies Workshop for
Journalist (Tuscon AZ, Dec 8) |
2002 |
Short Course director: UAB Birmingham:
Design and Analysis of Recombinant Inbred Strain
Experiments (all day course, June 18, 2002). |
1998 |
Course Lecturer: Short Course in Quantitative
Neuroanatomy. Society for Neuroscience, Los
Angeles CA |
1994–1996 |
Course director: Seminars in Neuroscience (NS821):
Graduate level. 40 contact hours, 10 to 15 students
per year |
1995 |
SGAEC Excellence in Teaching Award, University
of Tennessee (for NS822) |
1995 |
Short Course in Genetic Testing: Memphis city
schools service training for science high school
teachers (Summer 1995). 15 high school science
teachers |
1994–1995 |
Human and Mouse Genetics: City Labs program
for high school science teachers. 10 to 12 high
school science teachers |
1990–1996 |
Medical Embryology, University of Tennessee,
8 lectures on development of cardiovascular,
urogenital, and gastrointestinal systems. 8
lecture hours, ~120 first-year medical
students. |
1983–1989 |
Neuroscience-Neuroanatomy laboratory instructor,
Yale University. Team-taught first-year medical
students, roughly 20 contact hours, 25 students
per lab. |
1982 |
Course Director: Sensory Psychology, University
of California, Davis. 25 junior and senior psychology
majors. |
PERSONAL
|
Born April, 1952, Baltimore, USA. Married to
Kathryn A. Graehl (freelance editor), two sons
(15 and 20). |
Administrative
2001 – present |
Director: Complex Trait Consortium |
2000 – present |
Codirector: UT Center of Excellence in Genomics
and Bioinformatics |
2002 – present |
Member, Computing and Telecommunications Committee
of the Faculty Senate (C. Russell, chair). Chair:
Research Computing subcommittee. |
2002 – present |
University of Tennessee Research Foundation
Task Force Subcommittee (T. Ballard,
chair) |
2001 – 2002 |
Section Coordinator for the Visual and Auditory
Systems research section. Center for Neuroscience |
1999 – present |
Tennessee Mouse Genome Consortium, Scientific
Steering Committee |
1999 – 2001 |
Member: Promotion and Tenure Committee, Department
of Anatomy and Neurobiology |
1999 – present |
Scientific Advisory Board: Tennessee Mouse Genome
Consortium |
1998 |
Chair: Promotion and Tenure Committee, Department
of Anatomy and Neurobiology |
1998 – present |
Member: Department of Anatomy and Neurobiology
Space and Research Committee |
1997 – present |
Member: Department of Anatomy and Neurobiology
Advisory Council |
1997 – present |
Member: University of Tennessee, Graduate Health
Sciences Electronic Thesis and Dissertation
Advisory Committee |
1997 – 1999 |
Member: Center for Neuroscience: Graduate Student
Recruitment Committee |
1990 – 1997 |
Member: University of Tennessee, Graduate Health
Science School, Policy Subcommittee |
1995 – 1997 |
Member: University of Tennessee, Graduate Health
Science School, Graduate Studies Council |
1990 – 1994 |
Member, University of Tennessee library committee
member |
1990 – 1996 |
Member: Department of Anatomy and Neurobiology:
Graduate student admissions and policy committee |
Graduate Students and Postdoctoral Fellows
Dennis Rice |
Ph.D., 1996. University of Tennessee. Dr. Rice
is currently a Senior Scientist in Neurology
at Lexicon Genetics, Woodlands, Texas |
Richelle C. Strom |
Ph.D., 1999. University of Tennessee. Dr. Strom
is now a Postdoctoral Fellow with Prof. Ruben
Adler, Johns Hopkins University |
Dale Hogan, Ph.D. |
NRSA NEI Postdoctoral fellow, 1992–1996.
Currently a Research Associate with Mark Opp,
Department of Psychiatry and Behavior, University
of Texas Medical Branch, Galveston
Guomin Zhou, M.D., Ph.D.: Research fellow, 1997–1999.
G. Zhou is Chairman and Professor of Histology
and Embryology at Fudan University, Shanghai,
China |
Lu Lu,, M.D. |
Research fellow, 1999–2001. Dr. Lu is
an Associate Professor in Histology and Embryology
at the Medical University of Nantong, China.
He is also an Assistant Professor at the University
of Tennessee Health Science Center. |
David C. Airey, Ph.D. |
NRSA, NEI Postdoctoral
fellow, April 1999–July 2001. Dr. Airey
received his Ph.D. from Cornell University in
1999. He is currently a postdoctoral fellow
with Dr. Elaine Sanders-Bush at Vanderbilt. |
Elissa J. Chesler, Ph.D |
Research fellow, July
2002–present. |
Jeremy Perice, Ph.D. |
Research
fellow, June 2003-present |
Anand Kulkarni, M.D. |
Research fellow, Nov 1999–Nov
2000. Currently a physician in the Memphis area. |
Siming Shou, Ph.D. |
Postdoctoral
fellow, September 2001–2002. |
Emmanuel Gilissen ,Ph.D. |
Postdoctoral fellow
(1996–1997, with John Allman at Caltech).
Emmanuel is now on the faculty of paleontology,
University of the Witwassersrand, South Africa. |
Kathryn Ryder |
M.D. dissertation, Yale University School of
Medicine, 1987. Dr. Ryder is currently an assistant
professor, Department of Medicine at University
of Tennessee Health Science Center. |
Michael Borodkin |
M.D. dissertation, Yale University School of
Medicine, 1989 |
Ph.D., M.S. Committees
|
C. J. Jeon, Ph.D. in Neuroscience, 1992 |
|
Angela R. Howe, Ph.D. in Neuroscience, 1994 |
|
Vandana Menon, Ph.D. in Physiology, 1996 |
|
Qing Tang, Ph.D. in Anatomy and Neurobiology,
June 1996 |
|
Toya H. Kimble, Ph.D. in Anatomy and Neurobiology,
Jan 2003 |
|
Loren Martin, Ph.D. candidate in Anatomy and
Neurobiology, Nov 2000 |
|
Kathryn Ryder M.D. MS in Epidemiology, UTHSC
2002 |
|
Alessandro Iannaccone M.D., MS in Epidemiology,
UTHSC 2002 |
|
Félix Vázquez-Chona, candidate
in Anatomy and Neurobiology |
ORIGINAL PAPERS with citation analysis
After some of these papers I have included a
citations count. A paper‘s impact factor
is the number of citations divided by years
since publication. To provide some context,
papers published in Science and Nature are cited
an average of 5 times a year over a 15 year
period. Journal of Neuroscience articles are
typically cited 4.4 times a year, Journal of
Comparative Neurology articles, 3.7 times a
year (see The Scientist, Feb. 2, 1998, p. 11).
A substantial number of these papers are available
online at <www.nervenet.org>. |
1. |
Williams RW, Chalupa LM
(1982) Prenatal development of retinocollicular
projections in the cat: An anterograde tracer
transport study. Journal of Neuroscience
2: 604–622. Citations = 1983:5, 85:7,
86:13, 87:11, 88:10, 89:9, 90:7, 91:5, 92:2,
93:10, 94:2, 95:4, 96:2 (14 year total = 87).
Revised and updated text at <http://nervenet.org/papers/SC1982.html>. |
2. |
Stone, J, Rapaport DH,
Williams RW, Chalupa LM (1982) Uniformity of
cell distribution in the ganglion cell layer
of prenatal cat retina: Implications for mechanisms
of retinal development. Developmental
Brain Research 2: 231–242. Citations =
1983:12, 84:8, 85:12, 86:11, 87:14, 88:9, 89:9,
90:3, 91:2, 92:2, 93:2, 94:1, 95:1, 96:3 (total
= 89; 84 in first decade). |
3. |
Williams RW, Bastiani MJ,
Chalupa LM (1983) Loss of axons in the cat optic
nerve following fetal unilateral enucleation:
An electron microscopic analysis. Journal
of Neuroscience 3: 133–144. Citations
= 1983:7, 84:10, 85:12, 86:19, 87:12, 88:7,
89:3, 90:2, 91:3, 93:3, 94:2, 95:3, 96:4 (total
= 87, 78 in first decade). |
4. |
Williams RW, Chalupa LM
(1983) An analysis of axon caliber within the
optic nerve of the cat: Evidence of size groupings
and regional organization. Journal of
Neuroscience 3: 1554–1564. Citations =
1984:1, 85:8, 86:8, 87:5, 88:2, 89:4, 90:3,
91:0, 92:1, 93:4, 94:4, 95:6, 96:2 (total =
46, 38 in first decade). |
5. |
Williams RW, Chalupa LM
(1983) Development of the retinal pathway to
the pretectum of the cat. Neuroscience
10: 1249–1267. Citations = 1984:2, 85:4,
86:4, 87:5, 88:3, 89:2, 90:0, 91:4, 92:2, 93:1,
94:1, 95:0, 96:0 (total = 28, 27 in first decade). |
6. |
Chalupa LM, Williams RW,
Hughes MJ (1983) Visual properties of neurons
in the tectorecipient zone of the cat’s
lateral posterior-pulvinar complex: A comparison
with the superior colliculus. Journal
of Neuroscience 3: 2587–2596. Citations
= 1984:1, 85:1, 86:3, 87:5, 88:5, 89:5, 90:3,
91:5, 92:0, 93:3, 94:1, 95:1, 96:1 (total =
39; 36 in first decade). |
7. |
Chalupa, LM, Williams RW
(1984) Organization of the cat’s lateral
geniculate nucleus following interruption of
prenatal binocular competition. Human
Neurobiology 3: 103–107. Citations = 1985:4,
86:7, 87:0, 88:5, 89:4, 90:2, 91:0, 92:3, 93:5,
94:2, 95:2, 96:2 (total = 36, 32 in first decade). |
8. |
Chalupa LM, Williams RW,
Henderson Z (1984) Binocular interaction in
the fetal cat regulates the size of the ganglion
cell population. Neuroscience 12: 1139–1146.
Citations = 1985:5, 86:7, 87:5, 88:8, 89:4,
90:1, 91:0, 92:1, 93:5, 94:1, 95:6, 96:1 (total
= 44, 43 in first decade). <nervenet.org/papers/SC1982.html> |
9. |
Williams RW, Rakic P (1985)
Dispersion of growing axons within the optic
nerve of the embryonic monkey. Proceedings
of the National Academy of Science USA 82: 3906–3910.
Citations = 1986:9, 87:9, 88:8, 89:4, 90:4,
91:3, 92:4, 93:2, 94:2, 95:4, 96:6 (total =
55; 55 in first decade). <nervenet.org/papers/dispersion85.html> |
10. |
Williams RW, Crabtree,
JW, Chalupa LM, Spear PD, Kornguth SE (1985)
Selectivity of antibody-mediated destruction
of retinal ganglion cell axons. Brain
Research 336: 57–66. Citations through
1996: total = 6. |
11. |
Williams RW, Bastiani
MJ, Lia B, Chalupa LM (1986) Growth cones, dying
axons, and developmental fluctuations in the
fiber population of the cat’s optic nerve.
Journal of Comparative Neurology 246: 32–69.
Citations 1987:18, 88:22, 89:17, 90:19, 91:11,
92:8, 93:11, 94:10, 95:10, 96:7 (total = 133).
<nervenet.org/papers/Cat86.html>. |
12. |
Lia B, Williams RW, Chalupa
LM (1986) Does axonal branching contribute to
the overproduction of optic nerve fibers during
early development of the cat’s visual
system. Developmental Brain Research 25:296–301.
Citations through 1996: total = 14. |
13. |
Lia B, Williams RW, Chalupa
LM (1987) Formation of retinal ganglion cell
topography during prenatal development. Science
236:848–851. Citations 1987:1, 88:7, 89:10,
90:2, 91:5, 92:7, 93:1, 94:0, 95:2, 96:2 (total
= 37). |
14. |
Williams RW, Rakic P (1988)
Elimination of neurons from the lateral geniculate
nucleus of rhesus monkeys during development.
Journal of Comparative Neurology 272:424–436.
Citations = 1989:4, 90:11, 91:5, 92:7, 93:9,
94:5, 95:3, 96:12 (total = 56). <nervenet.org/papers/RHESUS_LGN.html> |
15. |
Williams RW, Rakic P (1988)
Three-dimensional counting: An accurate and
direct method to estimate cell numbers in sectioned
material. Journal of Comparative Neurology
278:344–352. Citations = 1989:4, 90:9,
91:6, 92:7, 93:9, 94:4, 95:3, 96:12 (total =
64). <nervenet.org/papers/3DCounting.html> |
16. |
Wikler KC, Williams RW,
Rakic P (1990) Photoreceptor mosaic: Number
and distribution of rods and cones in the rhesus
monkey retina. Journal of Comparative Neurology:297:499–508.
Citations = 1991:6, 92:5, 93:1, 94:4, 95:5,
96:10 (total = 31). |
17. |
Williams RW, Borodkin M, Rakic
P (1991) Growth cone distribution patterns in
the optic nerve of fetal monkeys: Implications
for mechanisms of axonal guidance. Journal of
Neuroscience 11: 1081–1094. Citations
= 1992:4, 93:4, 94:3, 95:7, 96:6 (total = 24).
<nervenet.org/papers/GC91.html> |
18. |
Rakic, P., Suñer
I, Williams RW (1991) A novel cytoarchitectonic
area induced experimentally within the primate
visual cortex. Proceedings of the National Academy
of Science USA 88: 2083–2087. Citations
= 1992:8, 93:3, 94:7, 95:8, 96:7 (total = 33). |
19. |
Williams RW (1991) The
human retina has a cone-enriched rim. Visual
Neuroscience 6:403–406. Citations = 1992:?,
93:2, 94:1, 95:3, 96:3 (total = 9). |
20. |
Williams RW, Goldowitz
D (1992) Structure of clonal and polyclonal
cell arrays in chimeric mouse retina. Proceedings
of the National Academy of Science USA
89: 1184–1188. Citations = 19923:5, 94:3,
95:8, 96:5 (total = 21). |
21. |
Williams RW, Cavada C,
Reinoso-Suárez F (1993) Rapid evolution
of the visual system: A cellular assay of the
retina and dorsal lateral geniculate nucleus
of the Spanish wildcat and the domestic cat.
Journal of Neuroscience 13:208–228. Citations
= 1994:2, 95:7, 96:6 (total = 15). <nervenet.org
/papers/wildcat.html> |
22. |
Williams RW, Hogan D,
Garraghty PE (1994) Target recognition and visual
maps in the thalamus of achiasmatic mutant dogs.
Nature 367:637–639; and see New
and Views article by R.W. Guillery, Nature 367:597–598.
Citations = 1994:2, 95:6, 96:5 (total = 13).
<nervenet.org/papers/DOGLGNNature.html> |
23. |
Williams RW (1994) The Portable
Dictionary of the Mouse Genome: A personal database
for gene mapping and molecular biology. Mammalian
Genome: 5:372-375. Citations total = 5. See
<nervenet.org/main/ dictionary.html> |
24. |
Brilliant MB, Williams
RW, Conti C, Angel J, Holdener BC (1994) Mouse
chromosome 7. Mammalian Genome 5: S104–S123.
Citations = 1995:1, 96:18 (total = 19). |
25. |
Dell'Osso LF, Williams
RW (1995) Ocular motor abnormalities in achiasmatic
mutant Belgian sheepdogs: Unyoked eye movements
in a mammal. Vision Research: 35:109–116.
Citations 1996 = 2, 97 = (total = 2). |
26. |
Scheetz AJ, Williams RW,
Dubin MW (1995) Severity of ganglion cell death
during early postnatal development is modulated
by neuronal activity and binocular competition.
Visual Neuroscience 12:605–610. Citations
1996 = 0, 97 = (total = 0). |
27. |
Hogan D, Williams RW (1995)
Analysis of the retinas and optic nerves of
achiasmatic Belgian sheepdogs. Journal of Comparative
Neurology: 352:367–380. |
28. |
Rice DS, Williams RW,
Goldowitz D (1995) Genetic control of retinal
projections in inbred strains of albino mice.
Journal of Comparative Neurology 354: 459–469.
Citations 1996 = 4, 97 = (total = 4). |
29. |
Rice DS, Williams RW,
Harris B, Bailey PW, Davisson MT, Goldowitz
D (1995) Mapping the Bst mutation on mouse Chromosome
16: A model for human optic atrophy. Mammalian
Genome 6:546–548. Citations 1996 = 1,
97 = (total = 1). <nervenet.org/papers/Bst2.html>. |
30. |
Hogan D, Garraghty PE,
Williams RW (1996) Lamination and visual topography
in the lateral geniculate nucleus of normal
and achiasmatic dogs. European Journal of Anatomy
1:3–11. |
31. |
Ezer AD, Williams RW,
Goldowitz D (1996) Arbitrary primer PCR of dog
DNA with estimates of average heterozygosity.
Journal of Heredity 87:450–455. |
32. |
Goldowitz D, Rice DS,
Williams RW (1996) Clonal architecture of the
mouse retina. Progress in Brain Research 108:
2–15. |
33. |
Brilliant MH, Williams
RW, Holdener BC, Angel JM (1996) Mouse chromosome
7. Mammalian Genome 6: S135–S150. |
34. |
Hamvas R, Trachtulec Z,
Forejt J, Williams RW, Artzt K, Fischer-Lindahl
K., Silver LM (1996) Mouse chromosome
17. Mammalian Genome 6: S281–S299. |
35. |
Williams RW, Strom RC,
Rice DS, Goldowitz D (1996) Genetic and
environmental control of retinal ganglion cell
number in mice. Journal of Neuroscience 16:
7193–7205. <www.jneurosci.org/cgi/content/full
/16/22/7193> |
36. |
Rice DS, Tang Q, Williams
RW, Harris B, Davisson MT, Goldowitz D (1997)
Retinal ganglion cell loss and misdirect axon
growth associated with fissure defects in Bst
mutant mice. Investigative Ophthalmology and
Visual Science 38:2112–2124. |
37. |
Williams RW, Strom RC,
Goldowitz D (1998) Natural variation in neuron
number in mice is linked to a major quantitative
trait locus on Chr 11. Journal of Neuroscience
18:138–146. <www.jneurosci.org/cgi/content/ab
stract/18/1/138> <www.informatics.jax.org/bin/fetch_expt?13547
/TEXT> |
38. |
Williams RW, Holdener
BC, Angel JM, Oakey R, Hunter K (1998) Mouse
chromosome 7. Mammalian Genome 8:S136–159.
<www.informatics.jax.org/bin/ccr/index?year=1998> |
39. |
Strom, RC, Williams RW
(1998) Cell production and cell death in the
generation of normal variation in neuron number.
Journal of Neuroscience 18:9948–9953.
<www.jneurosci.org/cgi/content/abstract/18/23/
9948> |
40. |
Dell'Osso, LF Williams
RW, Jacobs JB, Erchul DM (1998) The congenital
and see-saw nystagmus in the prototypical achiasma
of canines: comparison to the human achiasmatic
prototype. Vision Research 38:1629–1641. |
41. |
Zhou G, Williams RW (1999)
Eye1 and Eye2: Gene loci that modulate eye size,
lens weight, and retinal area in mouse. Investigative
Ophthalmology and Visual Science 40:817–825.
<nervenet.org/papers/Eye1.html>. |
42. |
Williams RW (1999) A targeted
screen to detect recessive mutations that have
quantitative effects. Mammalian Genome 10:734–738.
<nervenet.org/papers/consomic.html> |
43. |
Zhou G, Williams RW (1999)
Mouse models for the analysis of myopia: an
analysis of variation in eye size of adult mice.
Optometry and Vision Science: 76:408–418.
<nervenet.org/papers/OVSMyopia.html>. |
44. |
Williams RW, Angel JM,
Holdener BC, Oakey R, Hunter K (1999) Mouse
chromosome 7. Mammalian Genome 10:947 <www.informatics.jax.org/bin/ccr/index?year=1999>. |
45. |
Dell'Osso LF, Hertle RW,
Williams RW, Jacobs JB (1999) A new surgery
for congenital nystagmus: effects of tenotomy
on an achiasmatic canine and the role of extraocular
proprioception. J Amer Acad Ped Ophthal Soc,
3:166–182. |
46. |
Toth LA, Williams RW (1999)
Circadian patterns of locomotor activity in
CXB recombinant inbred mice. Behavior Genetics
29:319–328. |
47. |
Toth LA, Williams RW (1999)
Strain-related differences in slow wave sleep
and rapid-eye-movement sleep in C57BL/6J and
BALB/c mice. Behavior Genetics 29:329–337. |
48. |
Toth LA, Williams RW (1999)
Circadian patterns of slow wave sleep in influenza-infected
C57BL/6 and BALB/c mice: A genetic analysis
using CXB recombinant inbred strains. Behavior
Genetics 29:339–348. |
49. |
Rice DS, Goldowitz D,
Williams RW, Hamre K, Johnson PT, Tan SS, Reese
BE (1999) Extrinsic modulation of retinal ganglion
cell projections: analysis of the albino mutation
in pigmentation mosaic mice. Developmental Biology
216:41–56. Online: <www.idealibrary.com/links/artid/dbio.1999.9467> |
50. |
Hogan D, Garraghty PE,
Williams RW (1999) Asymmetric connections, duplicate
layers, and reversed maps in the primary visual
system. Journal of Neuroscience 19: RC38:1–6
. www.jneurosci.org/cgi/content/full/3657 |
51. |
Kimble TDH, Williams RW
(1999) Structure of the cone photoreceptor mosaic
in the retinal periphery of adult humans: Analysis
as a function of age, sex, and hemifield. Anatomy
and Embryology, 201:305–316. |
52. |
Dell'Osso LF,
Hogan D, Jacobs JB, Williams RW (1999) Eye movements
in canine hemichiasma: Does human hemichiasma
exist? Neuro-ophthalmology 22:47–58. |
53. |
Angel JM, Williams RW (2000)
Mouse chromosome 7. Mammalian Genome 11: 948–949. |
54. |
Williams RW, Lu L, Kulkarni
A, Zhou G, Airey DC (2001) Genetic dissection
of the olfactory bulbs of mice: QTLs on chromosomes
4, 6, 11, and 17 modulate bulb size. Behavior
Genetics, 31:61–77. <nervenet.org/papers/OB/OB2000.html> |
55. |
Cook MN, Williams RW, Flaherty
L (2001) Anxiety-related behaviors in the elevated
zero maze are affected by genetic factors and
retinal degeneration. Behavioral Neuroscience,
115:468–476. |
56. |
Lu L, Airey DC, Williams RW
(2001) Complex trait analysis of the mouse hippocampus:
Mapping and biometric analysis of two novel
gene loci that modulate hippocampal size. Journal
of Neuroscience, 21:3503–3514. <nervenet.org/papers/hipp1.html> |
57. |
Rosen GD, Williams RW
(2001) Complex trait analysis of the mouse striatum:
Independent QTLs modulate volume and neuron
number. Biomed Central Neuroscience 2:5
<http://www.biomedcentral.com/1471-2202/2/5> |
58. |
Airey DC ,Lu L, Williams
RW (2001). Genetic control of the mouse cerebellum:
identification of quantitative trait loci modulating
size and architecture. Journal of Neuroscience,
21:5099–5109. <nervenet.org/papers/cerebellum2000.html> |
59. |
Hardy CL, Lu L, Nguyen P, Woodland
DL, Williams RW, Blackman MA (2001) Identification
of quantitative trait loci controlling activation
of TRBV4 CD8+ T cells during murine g-herpes
virus-induced infectious mononucleosis. Immunogenetics,
53: 395–400. |
60. |
Williams RW, Gu J, Qi
S, Lu L (2001) The genetic structure of recombinant
inbred mice: High-resolution consensus maps
for complex trait analysis. Genome Biology
2:46.1–46.18 <http://genomebiology.com/2001/2/11/research/0046/> |
61. |
Hsu, HC, Mountz JD, Williams
RW, Shelton BJ, Yang P, Matsuki Y, Xu X, Zhang
HG, Geiger H, van Zant G (2002) Age-related
change in thymic T-cell development is associated
with genetic loci on mouse chromosomes 1, 3,
and 11. Mech Ageing Dev,123:1145–1158. |
62. |
Zhou G, Strom RC, Giguere V,
Williams RW (2001) Modulation of retinal cell
populations and eye size in retinoic acid receptor
knockout mice. Molecular Vision, 7, www.molvis.org/molvis/v7/a36/ |
63. |
Geisert Jr EE, Williams RW, Geisert G, Maecker
HT, Deng J, Levy S (2002) Increased brain size
and glial cell number in CD81-null mice.
Journal of Comparative Neurology, 453:22–32. |
64. |
Airey DW, Lu L, Shou S, Williams RW (2002) Genetic
sources of individual differences in cerebellum.
The Cerebellum 1:233–240. |
65. |
Hitzemann R, Hitzemann B, Rivera S, Gatley J,
Thanos P, Lu L, Shou S, Williams RW (2002) Dopamine
D2 receptor binding, Drd2 expression and the
number of dopamine neurons in the BXD recombinant
inbred series: genetic relationships to alcohol
and other drug associated phenotypes. Alcoholism:
Clinical and Experimental Research 27:1–11. |
66. |
Grizzle WE, Mountz JD, Yang PA, Xu X, Sun S,
Van Zant GE, Williams RW, Hsu HC, Zhang HG (2002)
BXD recombinant inbred mice represent a novel
T-cell mediated immune response tumor model.
International Journal of Cancer 101:270–279. |
67. |
Cook R, Lu L, Gu J, Williams RW, Smeyne RJ (2003)
Identification of a single QTL, Mptp1, for susceptibility
to MPTP-induced substantia nigra pars compacta
neuron loss in mice. Molecular Brain Research
110:279–288. |
68. |
Hsu HC, Zhang HG, Li L, Mullinax C, Yang PA,
Wu Q, Wu Y, Sun S, Renda J, Xu X, Yang X, Lu
L, Van Zant G, Williams RW, Allison DB, Mountz
JD (2003) Age-related thymic involution in C57BL/6J
X DBA/2J recombinant inbred mice fits a negative
exponential regression model and maps to mouse
chromosome 9. Genes and Immunity In press. |
69. |
Hitzemann R, Malmanger B, Reed C, Lawler M,
Hitzemann B, Coulombe S, Buck K, Rademacher
B, Walter N, Polyakov Y, Sikela J, Williams
RW, Flint J, Talbot C (2003) A strategy for
integration of QTL, gene expression, and sequence
analyses Mammalian Genome, 733–747. |
70. |
Schaeffel F, Burkhardt E, Howland HC, Williams
RW (2003) Measurement of refractive state and
deprivation myopia in two strains of mice. Optometry
and Vision Science, XX:XXX–XXX. |
71. |
Peirce J, Chesler EJ, Williams RW, Lu L (2003)
Genetic architecture of the mouse hippocampus:
identification of gene loci with regional effects.
Genes, Brain and Behavior 2:238–252. |
72. |
Wang J, Williams RW, Manly KF (2002) WebQTL:
Web-based complex trait analysis. Neuroinformatics
1:299–308. |
73. |
Pollock GS, Robichon R, Boyd KA, Kerkel KA,
Kramer M, Lyles J, Ambalavanar R, Khan A, Kaplan
DR, Williams RW, Frost DO (2003) TRKB receptor
signaling regulates dynamics of developmental
retinal ganglion cell death but not final number.
Journal of Neuroscience,23: 10137–10145. |
74. |
Rosen GD, La Porte NT, Diechtiareff B, Pung,
CJ, Nissanov J, Gustafson C, Bertrand L, Gefen
S, Fan Y, Tretiak OJ, Manly KF, Parks MR, Williams
AG, Connolly MT, Capra JA, Williams RW (2003)
Informatics center for mouse genomics: the dissection
of complex traits of the nervous system. Neuroinformatics,
1:327–342. |
75. |
Chesler EJ, Wang J, Lu L, Qu Y, Manly KF, Williams
RW (2003) Genetic correlates of gene expression
in recombinant inbred strains: a relational
model system to explore neurobehavioral phenotypes.
Neuroinformatics, 1: 343–357. |
76. |
Seecharan DJ, Kulkarni AL, Lu L, Rosen GD, Williams
RW (2003) Genetic control of interconnected
neuronal populations in the mouse primary visual
system. Journal of Neuroscience, 23:11178–11188. |
77. |
Santos JB, Williams RW, Schauwecker PE (2003)
Genetic control of seizure-induced cell death
susceptibility in mice. in review. |
78. |
Chesler EJ, Lu L, Shou S, Qu Y, Wang J, Hsu
HC, Mountz JD, Manly KF, Threadgill DW, Williams
RW. Massively parallel analysis of mouse brain
gene transcription regulation and transcription
networks. Submitted Aug 22, 2003. |
79. |
Williams AG, Williams RW (2003) GenomeMixer;
A complex genetic cross simulator. Bioinformatics,
In press. |
80. |
Peirce J, Lu L, J. Gu , Silver LM, Williams
RW (2004) A new set of BXD recombinant
inbred lines from advanced intercross populations.
BMC Genetics. In press. |
81. |
Williams RW, Bennett B, Lu L, Gu J, DeFries
JC, Carosone-Link P, Rikke B, Belknap JK, Johsnon
TE (2004) Genetic structure of the LXS panel
of recombinant inbred mouse strains. Mammalian
Genome. In press. |
82. |
Baldwin NE, Chesler EJ, Krov S, Langsteon MA,
Snoddy JR, Williams RW, Zhang B (2004) Computational,
integrative and comparative methods for the
elucidation of gene regulatory networks. Workshop
on Algorithms in Bioinformatics (WABI 2004)
Bergen Norway. www.ii.uib.no/algo2004 |
REVIEWS, LETTERS, BOOK CHAPTERS
1. |
Chalupa LM., Williams RW (1984) Prenatal development
and reorganization in the visual system of the
cat. In Development of Visual Pathways in Mammals.
Stone J, Dreher B, Rapaport DH (eds) Alan
R Liss Inc, New York, pp 89–102.
Citations total through 1996 = 25. Full text
<nervenet.org/papers/CatRev84.html>. |
2. |
Chalupa LM, Williams RW (1985) Formation of
retinal projections in the cat. In Advances
in Neuronal and Behavioral Development. vol
1. (Aslin RN, ed): Norwood, New Jersey: Ablex
Publishing, pp 1–32. Citations total through
1996 = 5. |
3. |
Williams RW, Herrup K (1988) The control of
neuron number. Annual Review of Neuroscience
11: 423–453. Citations = 1988:3, 89:12,
90:14, 91:20, 22:14, 93:21, 94:11, 95:11, 96:12
(total = 118). Full text <nervenet.org/papers/NUMBER_REV_1988.html>. |
4. |
Williams RW. Goldowitz D (1992) Lineage versus
environment in embryonic retina: A revisionist
perspective. Trends in Neuroscience. 15:368–373.
Also see: Williams RW, Goldowitz D (1993) Lineage
versus environment in embryonic retina: Letters
to the editor. Trends in Neuroscience. 16:96–98.
Citations = 1993:6, 94:5, 95:11, 96:4 (total
= 25). Full text <nervenet.org/papers/TINS_1992.html>. |
5. |
Williams RW (1990) The primary visual system
does not care about Previc’s near-far
dichotomy. Why not? Behavioral and Brain
Sciences: 13: 557. |
6. |
Williams RW
(1992) A very rare congenital eye movement disorder
in Belgian sheepdogs. National Belgian Newsletter:
44:75. |
7. |
Williams RW, Strom RC, Zhou G, Yan Z (1998)
Genetic dissection of retinal development. Seminars
in Cell and Developmental Biology 9:249–255.
<nervenet.org/papers/retinarev.html>. |
8. |
Williams RW (1998) Neuroscience meets quantitative
genetics: Using morphometric data to map genes
that modulate CNS architecture. Short Course
in Quantitative Neuroanatomy (Morrison J, and
Hof P, eds) pp 66-78. Full text <nervenet.org/papers/ShortCourse98.html> |
9. |
Toth LA, Williams RW (1998). Genetic analysis
of complex quantitative traits using inbred
mice. Sleep Research Society Bulletin 4:50–56. |
10. |
Williams RW (2000).
Mapping genes that modulate mouse brain development:
a quantitative genetic approach. In: Mouse brain
development (Goffinet AF, Rakic P, eds). Springer,
New York, pp 21–49. <nervenet.org/papers/brainrev99.html> |
11. |
Belknap JK, Crabbe JC, Phillips
TJ, Hitzemann R, Buck KJ, Williams RW (2001)
Quantitative trait loci and genome-wide mutagenesis:
two phenotype-driven approaches to the dissection
of complex murine traits. Behavior Genetics
31: 5–15. |
12. |
Mountz JD, van Zant G, Zhang
H, Grizzle WE, Ahmed R, Williams RW, Hsu HC
(2001) Genetic dissection of age-related changes
in immune function in mice. Scandinavian
Journal of Immunology, 54:10–20. |
13. |
Airey DC, Williams
RW. (2002) Quantitative genetic perspectives.
Commentary to Finlay BL, Darlington RB, and
Nicastro N (2002) Developmental structure in
brain evolution. Behavioral and Brain Sciences
24: 279–280. |
14. |
Hunter K, Williams
RW (2002) Quantitative trait locus analysis
in cancer research. ILAR J 43: 80–88. |
15. |
Threadgill, Hunter
K, Williams RW (2002) Genetic dissection of
complex and quantitative traits: from fantasy
to reality via a community effort. Mammalian
Genome 13:175–178. |
16. |
Williams RW, Dubnau J, Enoch
MA, Flaherty L, Sluyter F, Gannon KS, Maxson
SC, Riedl CAL, Williams KD, Holmes A,
Bolivar VJ, Crusio WE (2002) Hot topics
in behavioral and neural genetics. Gene, Brain
and Behavior 1: 1–10. |
17. |
Williams RW, Glueck SB (2002) New views of gene
expression in the brain: Focus on “Gene
expression tomography.” Physiological
Genomics, 8:79. |
18. |
Williams RW (2002) Everyday bioinformatics:
map, microarrays and beyond. Bioinformatics
2002, a Society for Neuroscience Short Course
(Williams RW, Goldowitz D, eds), Society for
Neuroscience, pp. 1–10. |
19. |
Dell’Osso LF, Williams RW, Jacobs JB,
Hertle RW, FitzGibbon EJ, Thompson MA, Yang
D (2002) Novel surgery for mystagus: initial
trial results. Res to Prevent Blindness
16: 56–57. |
20. |
Williams RW, Flaherty L, Threadgill DW (2003)
The math of making mutant mice. Genes, Brain
and Behavior 2:191–200. |
21. |
Williams RW, Moody SA (2003) Developmental and
genetic control of cell number in the retina.
In: The Visual Neurosciences, eds. Chalupa LM
, Werner JS. MIT Press. Pp 65–78. |
22. |
Williams RW, Broman KW, Cheverud JM, Churchill
GA, Hitzemann RW, Hunter K, Mountz JD, Pomp
P, Reeves RH, Schalkwyk LC, Threadgill DW (2002)
A collaborative cross for high-precision complex
trait analysis. 1st Workshop Report of the Complex
Trait Consortium: Sept 2002. http://www.complextrait.org/Workshop1.pdf |
23. |
von Bartheld CS, Williams RW (2003) Measurement
of differential shrinkage or compression in
the z-axis of tissue sections. Current Protocols
in Neuroscience Unit 11.11–1.11.29 Suppl
24. |
24. |
von Bartheld CS, Williams RW (2003) Calibration
of counting methods by a limited and simple
3-D reconstruction of serial sections. Current
Protocols in Neuroscience Unit 11.11–1.11.29
Suppl 24. |
25. |
Williams RW, von Bartheld CS, Rosen GD (2003)
Counting cells in sectioned material—3D
counting, the optical disector, and Abercrombie’s
two-section comparison method. Current Protocols
in Neuroscience Unit 1.11.1–1.11.29 Suppl
24. |
26. |
Rosen GD, Williams RW (2003) Celloidin embedding
and cresyl violet staining. Current Protocols
in Neuroscience Unit 11.11–1.11.29 Suppl
24. |
27. |
Rosen GD, Williams RW (2003) Estimation of regional
volume from serial sections using point counting
and Cavalieri’s rule. Current Protocols
in Neuroscience Unit 1.11. |
28. |
Williams RW, Rosen GD (2003) Providing researchers
access to tissue banks. American Laboratory,
in press. |
29. |
Gardner D, Toga AW, Ascoli GA, Beatty J, Brinkley
AF, Dale AM, Fox PT, Gardner EP, George JS,
Goddard N, Harris KM, Herskovits EH, Hines M,
Jacobs GA, Jacobs RE, Jones EG, Kennedy DN,
Kimberg DY, Mazziotta JC, Miller P, Mori S,
Mountain DC, Reiss AL, Rosen GD, Rottenberg
DA, Shepherd GM, Smalheiser NR, Smith KP, Strachan
T, Van Essen DC, Williams RW, Song STC (2003)
Toward effective and rewarding data sharing.
Neuroinformatics, in press. |
30. |
Schaeffel F, Simon P, Feldkaemper M, Ohngemach
S, Williams RW (2003) Molecular biology of myopia.
Clinical and Experimental Optometry, 86: 295–307. |
31. |
The Complex Trait Consortium: Flaherty L, Abiola,
O., Angel, J. M., Avner, P., Bachmanov, A. A.,
Belknap, J. K., Bennett, B., Blankenhorn, E.
P., Blizard, D. A., Bolivar, V.,
Brockmann, G. A., Buck , K. J., Bureau, J-F.,
Casley, W. L., Chesler E. J., Cheverud, J. M.,
Churchill, G. A., Cook, M., Crabbe, J.
C., Crusio, W. E., Darvasi, A., de Haan, G.,
Demant, P., Doerge, R. W., Elliott, R. W., Farber,
C. R., Flint, J.,Gershenfeld, H., Gibson, J.
P., Gu, W., Himmelbauer, H., Hitzemann,
R., Hsu, H.-C., Hunter, K., Iraqi, F., Jansen,
R. C., Johnson, T. E., Jones, B. C., Kempermann,
G., Lammert, F., Lu, L., Manly, K. F., Matthews,
D. B., Medrano, J. F., Mehrabian, M.,
Mittleman, G., Mock, B. A., Mogil, J. S., Montagutelli,
X., Morahan, G., Mountz , J. D., Nagase,
H., Nowakowski , R. S., O'Hara, B. F., Osadchuk,
A. V., Paigen, B., Palmer, A. A., Peirce, J.
L., Pomp, D., Rosemann, M., Rosen, G.
D., Schalkwyk, L. C., Seltzer, Z.,
Settle, S., Shimomura, K., Shou, S., Sikela,
J. M., Siracusa, L. D., Spearow, J. L., Teuscher,
C., Threadgill DW, Toth LA, Toye AA., Vadasz
C. Van Zant, G.,Wakeland, E., Williams RW, Zhang,
H-G., Zou, F. The nature and identification
of quantitative trait loci: a community’s
view. Nature Genetics Reviews 4: 911–916. |
32. |
Nissanov J, Williams RW (2003) Mouse neuroinformatic
public resources. An invitation to end-users.
Neuroinformatics 1: 297–298. |
33. |
Williams RW (2003) A neuroscientist’s
guide to genomic resources. In: The Bioinformatics
of Brains: From genes and proteins to behavior
(Williams RW, ed) pp. 1–8. Washington,
DC: Society for Neuroscience. |
34. |
Williams RW (2003) WebQTL: a tour of transcriptional
networks. In: The Bioinformatics of Brains:
From genes and proteins to behavior (Williams
RW, ed) pp. 51–59. Washington, DC: Society
for Neuroscience. |
35. |
Williams RW (2003) Managing your lab data flux:
getting beyond Excel (Williams RW, ed) pp. 83–92.
Washington, DC: Society for Neuroscience. |
36. |
Zareparsi S, Hero A, Zack DJ, Williams RW, Swaroop
A (2004) Seeing the unseen: microarray-based
gene expression profiling in vision. Investigative
Ophthalmology and Vision Science, in press. |
37. |
Chesler EJ, Lu L, Wang J, Williams RW, Manly
KF (2004) WebQTL: Rapid exploratory analysis
of gene expression and genetic networks for
brain and behavior. Nature Neuroscience, 7:3–4. |
Web Sites
1. |
Williams
RW (1994) The Portable Dictionary of the Mouse
Genome. An electronic dictionary of gene loci
with map, phenotype, and strain distribution
data. <http://nervenet.org> January 1994–present. |
2. |
Williams
RW, Rosen GD, Williams, A. G. (1997) The Mouse
Brain Library and the Internet Atlas of the
Mouse Brain at <www.mbl.org> May 1997–present.
This is an Internet database of over 800 brains
imaged at high resolution. It includes a stereotaxic
atlas of the brain of strain C57BL/6J.
As of Jan. 2001, www.nervenet.mbl.mbl.html is
included in ISI Current Web Contents (CC Connect
TM). Reviewed in: Kaiser J (2000) Mouse Brain
Library: Netwatch Images selection. Science
289:211. |
3. |
Williams
RW, Cruz B, Connolly M; Capra JA (1999) iScope.
A motorized microscope that can be controlled
on the WWW. <zoom.utmem.edu > Aug 1999–present. |
4. |
Wang JT, Williams
RW, Manly KF (2002-present) WebQTL Project.
A system for rapidly analyzing transcriptional
networks. http://webqtl.roswellpark.org/search.html
and http://headmaster.utmem.edu |
RECENT ABSTRACTS (from 1999 onward only)
|
Williams RW (1999) Mapping QTLs that modify
the architecture of the mouse brain: a prelude
to behavioral analyses. Behavior Genetics Society
Abstracts 29: XX. |
|
Williams RW, Zhou G (1999) Genetic control of
eye size: A novel quantitative genetic approach.
Invest. Ophthalmol Vis Sci Suppl 40: S964. |
|
Toth LA, Williams RW (1999) A quantitative trait
locus for slow-wave sleep in influenza-infected
CXB recombinant inbred mice. World Fed Sleep
Res Soc. |
|
Airey DC, Lu L, Strom R, Zhou G, Gilissen E,
Williams RW (1999) Cerebellum-specific QTLs
in the mouse brain. Int Mouse Genome Conf 13:E9. |
|
Lu L, Airey DC, Zhou G, Williams RW (1999) New
murine hippocampus-specific QTL maps to distal
Chr 1. Int Mouse Genome Conf 13:E44. |
|
Williams RW, Kulkarni AL, Jones L,
Zhou G, Airey DC, Lu L (2000) Growth of the
olfactory bulbs is modulated by QTLs on chromosomes
4, 6, 11, and 17. Neuroscience Abstracts
26: 1088. |
|
Rosen GD, Williams RW (2000) Stereological and
quantitative genetic analysis of the mouse caudate
nucleus. Neuroscience Abstracts 26: 311. |
|
Kulkarni AL, Airey DC, Williams RW (2000)
Genetic architecture of the mouse retinogeniculate
system: a QTL analysis of numerical matching.
Neuroscience Abstracts 26: 1087. |
|
Airey DC, Lu L, Williams RW (2000) Gene loci
for mouse cerebellum and internal granule layer
size. Neuroscience Abstracts 26: 1087. |
|
Lu L Airey DC, Williams RW (2000) Complex trait
analysis of the mouse hippocampus. Neuroscience
Abstracts 26: 1087. |
|
Tharp R, Williams RW, Smeyne RJ (2000) Complex
trait analysis of susceptibility to MPTP-induced
Parkinsonism. Neuroscience Abstracts 26:
1286. |
|
Rosen GD, Williams AG, Capra JA, Connolly MT,
Cruz B, Lu L, Airey DC, Kulkarni A, Williams
RW (2000) The Mouse Brain Library @ www.mbl.org.
Int Mouse Genome Conference 14: 166. www.nervenet.org/papers/MBLabst2000.html |
|
Williams RW, Zhou G (2001) Development of genetic
models for myopia research: high resolution
mapping of a new set of loci that control eye
size in mice. Invest Ophthal Vis Sci Suppl 42:S
652. |
|
Manly KF and Williams RW (2001) WEBQTL—WWW
services for mapping quantitative trait loci.
Mouse Initiatives III. www.jax.org/courses/documents/mouse_init_0801.html |
|
Li L, Lu L, Williams RW, Waters RS (2001) Quantitative
analysis of the barrel field in somatosensory
cortex (S1) of inbred mice. Neuroscience Abstracts
27: 394.3. |
|
Lu L, Airey DC, Williams RW, 2001. Genetic architecture
of the mouse hippocampus: identification of
gene loci with regional effects. Neuroscience
Abstracts 27: 587.2. |
|
Goldowitz D, Rinchik E, Johnson D, Goss K, Snoddy
J, Ferkin M, Matthews D, Mittleman G, Hamre
K, Jablonski M, Williams R, and members of the
Tennessee Mouse Genome Consortium (2001) Regional
mutagenesis of the mouse genome and neural phenotypes:
Year1 Progress Report. Neuroscience Abstracts
27: 881.7. |
|
Wolfe C, Williams RW, Goldowitz D (2001) Genetic
determinants of neurogenesis in adult mice.
Neuroscience Abstracts 27: 587.1. |
|
Williams RW, Threadgill DW, Airey DC, Gu J,
Lu L (2001) RIX mapping: A demonstration using
CXB RIX hybrids to map QTLs modulating brain
weight in mice. Neuroscience Abstracts 27:
587.3. |
|
Threadgill DW, Airey DC, Lu L, Manly K, Williams
RW (2001) Recombinant inbred intercross mapping:
a new approach to extend the power of existing
mouse resources. Int Mouse Genome
Conf 15:50. |
|
Manly K, Williams RW (2001) WEBQTL—WWW
service for mapping quantitative trait loci.
Int Mouse Genome Conf 15:74. |
|
Shou S, Lu L, Williams RW (2001) Transcriptome
chromosome maps: a novel resource for complex
trait analysis of the mouse CNS. Internat Behav
Neural Genet Soc Abst 4:54. |
|
Williams RW, Threadgill DW, Manly KF, Rosen
GD, Shou S, Airey DC, Gu J, Lu L (2001) Integrated
complex trait analysis of brain and behavior
in mouse: near-term prospects for high-resolution
QTL mapping using large RI and RIX sets. Internat
Behav Neural Genet Soc Abst 4:62 |
|
Williams RW, Lu L, Wang XF, Qi S, Gu J, Jablonski
MM (2002) Mapping and initial characterization
of a spontaneous mutation affecting lens development
in RIIIS/J inbred mice. Invest Ophthalmol Vis
Sci Suppl 43: S XX. |
|
Bennett B, Johnson TE, Williams RW (2002) A
new panel of recombinant inbred strains from
ILS and ISS. Res Soc Alcoh meeting.XX: XXX. |
|
Watson R, Koratkar R, Lu L, Gu J, Fineegan AA,
Margan JL, Guz J, Williams RW, Siracusa LD (2002)
Expansion of the BXH RI series: derivation and
characterization of three new BXH recombinant
inbred lines and one new BXH recombinant congenic
line. Abst Amer Assoc Cancer Res XX: XXX. |
|
Erin L. Manning EL, True JM, Henckaerts E, Snoech
H, Geiger H, de Haan G, Lu L, Williams RW, Van
Zant G (2002) Genetic regulation of hematopoietic
stem cell telomere length in mice. Int Soc Exp
Hematol Abst XX: XXX |
|
Williams RW, Shou S, Lu L, Qu Y, Wang J,
Manly K, Chesler EJ, Hsu HC, Mountz J, Threadgill
D (2002) Genomic analysis of transcriptional
networks: combining microarrays with complex
trait analysis. Int Complex Trait Consortium
Conf 1: http://www.complextrait.org/ctcsche/start.html |
|
Bennett B, Johnson TE, Williams RW (2002) A
new panel of recombinant inbred strains from
ILS and ISS. Int Complex Trait Consortium
Conf 1: http://www.complextrait.org/ctcsche/start.html |
|
Chesler EJ, Rodriguez-Zas SL, Williams RW, Mogil
JS (2002) “In Silico” mapping of
complex traits in inbred mice? Int
Complex Trait Consortium Conf 1: http://www.complextrait.org/ctcsche/start.html |
|
Manly K, Meer JM, Wang J, Williams RW (2002)
QTX and WebQTL: software for analysis of complex
traits. Int Complex Trait Consortium Conf
1: http://www.complextrait.org/ctcsche/start.html |
|
Hsu HC, Zhang HG, Li L, Mullinax CL, Lu L, VanZant
G, Williams RW, Allison DB, Mountz JD (2002)
Age-related thymic involution in C57BL/6J X
DBA/2J recombinant inbred mice fits a negative
exponential regression model and maps to mouse
chromosome 9. Int Complex Trait Consortium
Conf 1: http://www.complextrait.org/ctcsche/start.html |
|
Grizzle WE, Mountz JD, Yang PA, Xu X, Sun S,
Van Zant GE, Williams RW, Hsu HC, Zhang HG (2002)
Recombinant inbred mice represent a novel T-cell
mediated immune response tumor model. Int
Complex Trait Consortium Conf 1: http://www.complextrait.org/ctcsche/start.html |
|
Jablonski MM, Wang XF, Lu L, Goldowitz D, Williams
RW (2002) Regional mutagenesis of the mouse
genome: ocular phenotypes. Soc. Neurosci Abst. |
|
Williams RW, Shou S, Lu L, Qu Y, Manly KF, Wang
J, Chesler E, Hsu HC, Mountz J, Threadgill DW
(2002) Massively parallel QTL mapping of microarray
data reveals mouse forebrain transcriptional
networks. Soc. Neurosci Abst. |
|
Williams RW, Manly KF, Shou S, Chesler E, Hsu
HC, Mountz J, Wang J, Threadgill DW, Lu L (2002)
Massively parallel complex trait analysis of
transcriptional activity in mouse brain. International
Mouse Genome Conference 16: 46 |
|
Lu L, Gu J, Threadgill D, Williams R (2002)
Complex trait analysis of mice hippocampus using
CXB RIX mapping method. International Mouse
Genome Conference 16:88. |
|
Manly KF, Wang J, Shou S. Qu Y, Chesler E, Lu
L, Hsu HC, Mountz JD, Threadgill D, Williams
RW (2002) QTL mapping with microarray expression
data. International Mouse Genome Conference
16: 88. |
|
Hitzemann R, Williams R, Reed C (2002) The integration
of functional genomics and QTL analysis. International
Mouse Genome Conference 16: 122. |
|
Goldowitz D, Rinchik E, Johnson d, Goss K, Hamre
K, Matthews D, Ferkin M, Mittleman G, Montine
T, Jablonsky M, Williams R, Snoddy J, Miller
D (2002) Regional mutagenesis of the mouse genome
and neural phenotypes. International Mouse Genome
Conference 16:120. |
|
Chesler EJ, Rodrigues-Zas Sl, Williams RW, Mogil
JS (2002) Extension and evaluation of “in
silico” mapping of complex traits. International
Mouse Genome Conference 16:39. |
|
Chesler EJ, Wang J, Lu L, Manly KF Williams
RW (2003) Genetic correlations of gene expression
with neurobehavioral traits in a recombinant
inbred mapping panel. Int. Behav Neurosci. |
|
Hsu HC, Li L, Yi N, Zhang, HG, Yang PA, Wu Q,
Zhou J, Lu L, Allison AB, Williams RW, Mountz
JD (2003) Genomic analysis of age-related
thymic involution. Am Assoc Immunol. |
|
Chesler EJ…. Williams RW (2003) Web-based
QTL mapping and genetic correlation analysis
of gene expression and alcohol-related traits
in BXD strains. Res Soc Alcohol |
|
Williams RW, Xu J, Zhai H, Lu L (2003) Complex
trait analysis of retinal horizontal cell number.
ARVO Abst 5576. |
|
Geisert EE…. Williams RW (2003) The control
of gene expression following injury in the rat
retina; QTL and PCA. ARVO Abst 3594. |
|
Bystrykh L, Weersing E, DontjeB, Vellenga E,
Wang J, Manly KL, Williams RW, Cooke M, de Haan
G (2003) Genetical genomics to identify gene
pathways regulating hematopoietic stem cells.
CTC 2. |
|
Osadchuk AV, Airey DC, Lu L, Threadgill DW,
Williams RW (2003) A novel approach to genetically
dissection complex quantitative traits using
the RIX diallel cross of recombinant inbred
strains. CTC 2. |
|
Manly KF, Wang J, Williams RW (2003) WebQTL;
Complex trait analysis beyond QTL mapping. CTC
2. |
|
De Koning DJ, Carlborg O, Williams RW, Lu L,
Haley C (2003) Epistatic QTL for gene expression
in mice: potential for BXD expression data.
CTC 2. |
|
Chesler EJ, Wang J, Lu L, Manly KF, Williams
RW (2003) Genetic correlations and associative
networks for CNS transcript abundance and neurobehavioral
phenotypes in a recombinant inbred mapping panel.
CTC 2. |
|
Chesler EJ, Wang J, Lu L, Peirce JL, Qu S, Manly
KF, Williams RW (2003) Web-based QTL mapping
and genetic correlation analysis of gene expression
and alcohol-related traits in BXD strains. Alcoholism
Clin Exp Res 27:P 125A |
|
Fernandes A, Yin H, Byron B, Iuvone PM, Schaeffel
F, Williams RW, Pardue MT (2004) Effects of
form deprivation on eye size and refraction
in C57BL/6J mice. IOVS |
|
Pardue MT, Yin H, Irving B, Schaeffel F, Williams
RW, Fernandes A (2004) The refractive state
of a mouse model of clinical disease associated
with high myopia. IOVS |
|
Aronow B, Jegga A, Kong S, Williams S, Hutton
J, Ebert C, Gupta A, Chesler EJ, Lu L, Shou
S, Qu Y, Wang J, Manly KL, Williams RW, Threadgill
DW (2004) Discovering transcriptional regulatory
networks by correlationg quantitative trait
loci that modify tissue specific gene expressison
with the occurrence of phylogenetically conversed
cis element clusters. |
|
Boughter J, St. John S, Williams RW, Lu L (2004)
Genetic control of lick rate in mice.
Association for Chemoreception Sciences. |
News and Coverage
|
Blakeslee S (1993) Evolution of tabby cat mapped
in brain study. The New York Times, Tuesday
January 12 issue, Section B5. |
|
Simion L (1993) Al micio si e rimpicciolito
il cervello. Il Corriere Della Sera (Milan newspaper)
Jan 31 issue. |
|
Oliwenstein L (1993, May issue) Brain Donors.
Discover 14:18. |
|
Guillery RW (1994) No crossing at the crossing.
A New and Views article. Nature 367:597–598
(this review considers a paper by Williams et
al. 1994). |
|
Mansfield BK (1994) Mouse gene data files available
from U.T. Memphis. Human Genome News, May 1994. |
|
Takahashi JS (1994) Forward and reserve genetic
approaches to behavior in the mouse. Science
264: 1724-1733. This review contains a brief
description of the Portable Dictionary of the
Mouse Genome (pp. 1728-1729) |
|
Kaiser J (2000) Mouse Brain Library: Netwatch
Images selection. Science 289:211. |
|
Memphis Commercial Appeal: July 9, 2001. Front
page photo of Abigail Haynes working in R. Williams
laboratory (by Lance Murphey). |
|
Memphis Business Journal: June15–21, 2001.
Vol. 23 No. 7. Photograph of Dr. Michael Dockter
in R. Williams laboratory (by Alan Howell). |
|
Memphis Business Journal: Jan 15–21, 2002.
Vol. 24 No. X. RW cited in article on Genome
Explorations. |
|
Commercial Appeal: May 15, 2002: World’s
scientists sniff trail of complex traits. RW
cited in article as organizer. Page A11. |
|
Providing Broad Access to Tissue Banks: on the
Science & Technology site at Apple Inc.
http://www.apple.com/scitech/appletech/dv/utic/
(posted 2002) |
|
iScope, You scope, We all scope a mouse brain:
AAAS News Release, Feb 17, 2003 by Monica
Amarelo. |
|
Which Gene Influences What? Data Desk Aids in
Gene Mapping: DataDescription Inc., by
Holly M. Bailey, July , 2003, http://www.datadesk.com/company/profiles/williams.shtml |
|
Building a Better Mouse Database. Bio IT World
June 15, 2003 issue. http://www.bio-itworld.com/archive/061503/mouse_sidebar_2646.html
and see http://www.bio-itworld.com/archive/061503/mouse.html |
|
Vogel, G (2003) Geneticist Dream of 1001 Complex
Mice. Science 301:456–457. |
|
Mouse Brains — FileMaker & Excel
by Mike Nelson for Bio-IT World |
|