Curriculum Vitae Updated on April 2015

Lu LU

Office Address:

Department of Genetics, Genomics and Informatics

University of Tennessee Health Science Center

855 Monroe Avenue

Memphis TN 38163

Phone: 901-448-7557 (O); 901-448-7018 (Lab)

E-Mail: lulu@uthsc.edu

EDUCATION

1998-1999: Postdoctoral Research Fellow, Department of Medicine, College of Physicians & Surgeons, Columbia University, New York

1984-1987: M.S. in Neuroscience, Shanghai Medical University, Shanghai

1977-1982: M.D. in Medicine, Nantong Medical College, Nantong

ACADEMIC APPOINTMENTS

1987–1989 Lecturer in Histology and Embryology, Shanghai Medical University

1989–1998 Chairman, Associate Professor, Dept. of Histology and Embryology, Nantong University

2001–2006 Assistant Professor, Department of Anatomy and Neurobiology, University of Tennessee Health Science Center

2006–2012 Associate Professor, Department of Anatomy and Neurobiology, University of Tennessee Health Science Center

2012–present Professor, Department of Anatomy and Neurobiology, Department of Genetics, Genomics and Informatics, University of Tennessee Health Science Center

MAIN RESEARCH INTERESTS

The focus of my laboratory is on the examination of the role of genetics in a number of nervous system-related processes including the development of neuronal populations, the genetic underpinnings of neuroanatomical/structural features of the brain, the genetic control over responses to alcohol and stress, and more recently genetic basis of variation of gene expression. The types of studies conducted in my lab range from a more global perspective in identifying relevant regions of the genome that control phenotypic differences among genetically distinct organisms to more targeted research where the role of specific genes is evaluated. In these studies, I use a combination of molecular biological, behavioral, morphological and bioinformatic methods, and genetics and system biology strategy. In the past, the goal of genetic research was to identify the critical gene involved in special phenotype. However, it has become clear that individual gene does not work in isolation but in combination with other genes necessitating the identification of the relevant gene networks. Thus, much of the work in my lab is focused on evaluating phenotypes with the ultimate goal of identifying the genetic networks that control each phenotype. More recently, I have begun to examine changes in microRNAs to more completely assess the genetic networks that underlie these complex processes.

PROFESSIONAL SOCIETY MEMBERSHIPS

Research Society Alcoholism

Society for Neuroscience

Behavior Genetics Association

International Mammalian Genome Society

International Complex Trait Consortium

International Behavioral and Neural Genetics Society

EDITORIAL APPOINTMENTS

2010-present: Editorial Board of Degenerative Neurological and Neuromuscular Disease

2012-present: Editorial Board of Frontiers in Neurogenomics

INSTITUTIONAL SERVICE

2009-present: Member of Space and Resources Committee of Anatomy and Neurobiology Department, University of Tennessee Health Science Center

2008-present: Member of the CITG Mouse Resource Committee at UTHSC

2005- present: Member of Molecular Resource Center Internal Advisory Committee, University of Tennessee Health Science Center

2006-present: Head of Gene Expression and Genotype Core, Center of Integrative and Translational Genomics (CITG), University of Tennessee Health Science Center.

RESEARCH SUPPORT

Ongoing Research Support

1. R01EY021200-01 (Multiple PI: Lu Lu & Monica Jablonski) 06/01/11 - 05/30/16

NIH/NIE

Genetic Modulation of Glaucoma

In this proposal, we are using cutting-edge genetics and genomics tools to define the genetic modulation of ganglion cell death and optic nerve degeneration in glaucoma models. We are exploiting our BXD family of strains. We are also generating molecular and statistical models of glaucoma susceptibility and severity using bidirectional translation of clinical and laboratory discoveries.

2. R01ES022614 (Multiple PI: Byron Jones & Lu Lu) 05/12/14~02/28/19

NIH/NIEH

"Neural toxicity of paraquat is related to iron regulation in the midbrain"

In this project we use an innovative systems genetic approach to examine the effect of genotype, dietary iron, and paraquat dose on iron influx in the SNc and related neurotoxicity.

3. R01AA021951 (Multiple PI: Byron Jones & Lu Lu) 09/26/14~09/25/19

NIH/NIAAA

Genetics of Chronic Mild Stress and Alcohol Consumption

The goal of this project is to identify genes and gene networks that are related to stress-related alcohol consumption and that are syntenic with the human genome.

4. R01EY017841-02 (PI: Eldon Geisert) 12/10/07 ~ 12/31/17

NEI

Modulators of Retinal Injury

The long-term goal of this project is to define genetic networks controlling susceptibility and resistance of the retina to optic nerve damage and to characterize the early molecular signatures associated with these changes.

Role: Co-Investigator

5. U01 AA013499-11 (PI: Robert Williams) 02/01/12 ~ 01/31/17

NIH/NIAAA

Systems Genetics of Alcohol Response and Stress Effects in CNS

This project is a part of the INIA STRESS Consortium submitted in response to RFA-AA-11-006 entitled Integrative Neuroscience Initiative on Alcoholism. This is a renewal application proposing to use new genomic methods to understand much more about differential vulnerability to alcohol and stress and molecular targets using diverse BXD strains of mice.

Role: Co-Investigator

6. R01AA017590 (PI: Robert Williams) 12/01/12 ~ 11/31/17

NIH/NIA

Translational Systems Genetics of Mitochondria, Metabolism, and Aging

Genetic analysis of aging and metabolism on normal and high fat diet in murine populations with associated analysis of human populations.

Role: Co-Investigator

Completed Research Support

UTHSC pilot fund (Lu Lu, PI) 05/01/13 ~ 04/30/14

UTHSC

Genetic analyses of ethanol-mediated stress reduction

This project will test the hypothesis that microRNAs have a critical role in mediating the interaction between stress and ethanol as well as mediating genetic differences in responses to stress and/or alcohol exposure.

R01AA014425 (Lu, Lu, PI) 06/01/04 – 05/31/11 NIAAA

Genetic Analysis of Ethanol-Mediated Stress Reduction

The aim of this project is to understand the genetic basis of variation in responses to stress, ethanol, and their combination by examining changes in gene expression and upstream modulation of expression differences under four conditions.

R21 NS066166 (Nowak, Thad, PI, Role: Co-Investigator) 07/01/11 - 06/30/13 NIH/NINDS

Genetics of stroke vulnerability in mice

The aim of this project is to systematically define how brain injury varies after experimental stroke across a large panel of mouse strains having known variations in genome sequence.

U01AA017590 (Williams, Robert, PI, Role: Co-Investigator) 09/30/07 - 09/29/12 NIH/NIAAA

Systems Genetics of the HPA

Genetic dissection and reassembly of molecular networks involved in HPA axis responses in the BXD.

W81XWH-09-1-0391 (Byrne, Gerry, PI, Role: Co-Investigator) 06/01/09 - 05/31/12 DOD/US Army

Host Genes and Resistance/Sensitivity to Military Priority Pathogens

Enhance combat readiness and performance in the face of pathogen threats. Develop novel resources and conduct extensive experiments to understand the many factors that influence susceptibility to select pathogens.

R073003343 (Kempermann, Gerd, PI, Role: Sub-contract PI) 11/01/09 - 10/31/11 Dresden, Germany

Adult hippocampal neurogenesis

R21AI081050 (Miyairi, Isao, PI, Role: Co-Investigator) 06/01/09 - 06/30/11 NIH/NIAID

System genetics of immune pathways induced by Chlamydia

The goal of this project is to predict the outcome of infectious diseases based on the genotype and gene expression data of the host.

R01EY017841 (Geisert, Eldon, PI, Role: Co-Investigator) 12/10/07 - 12/31/11 NIH/NEI

Modulators of Retinal Injury

U01 AA016666, (Goldowitz, Daniel, PI, Role: Co-Investigator). 02/01/07 - 01/31/11 NIH/NIAAA/INIA

Mouse Resources Core

The goal of this project is to create new recombinant inbred strains for ethanol research community and help genetic mapping for ethanol related phenotypes.

PUBLICATIONS

Peer-Reviewed Papers (only list the papers since I have worked at UTHSC in 1999)

1. Williams RW, Airey DC, Kulkarni A, Zhou GM, Lu L: Genetic dissection of olfactory bulbs of mice: QTLs on four chromosomes modulate bulb size. Behavioral Genetics, 2001, 133:61-77;

2. Lu L, Airey DC, Williams RW: Complex trait analysis of the hippocampus: Mapping and biometric analysis of two novel gene loci with specific effects on hippocampal structure in mice. Journal of Neuroscience, 2001, 21:3503-3514

3. Airey DC, Lu L, Williams RW: Genetic control of the mouse cerebellum: identification of quantitative trait loci modulating size and architecture. Journal of Neuroscience, 2001, 21:5099-5109

4. Hardy CL, Lu L, Nguyen P, Woodland DL, Williams RW, Blackman MA: Identification of quantitative trait loci controlling activation of TRBV4 CD8+ T cells during murine gamma-herpesvirus-induced infectious mononucleosis. Immunogenetics, 2001, 53(5): 395-400

5. Williams RW, Gu J, Qi SH, and Lu L: The genetic structure of recombinant inbred mice: High-resolution consensus maps for complex trait analysis. Genome Biology 2001, 2(11): research 0046.1-0046.18

6. Lu L, Mei DF, Gustain DE, Zwas D, Homma S, Yi GH, Wang J: Exercise training normalized altered calcium handling proteins during development of heart failure. J Appl Physiology 2002, 92:1524-1530

7. Airey DC, Lu L, Shou SS, Williams RW: Genetic sources of individual differences in the cerebellum. The Cerebellum, 2002, 1:233-240

8. Cook R*, Lu L*, Gu J, Williams RW, Smeyne RJ: Identification of a single QTL, Mptp1, for susceptibility to MPTP-induced substantia nigra pars compacta neuron loss in mice. Mol Brain Res. 2003, 110(2): 279-88; (co-first author)

9. Hitzemann R, Hitzemann B, Rivera S, Gatley J, Thanos P, Lu L, Shou S, and Williams R: Dopamine D₂ receptor binding, Drd2 expression and the number of dopamine neurons in the BXD recombinant inbred series: genetic relationships to alcohol and other drug associated phenotypes. Alcoholism: Clinical and Experimental Research 2003; 27(1):1-11

10. Peirce J, Chesler EC, Williams RW, Lu L: Genetic architecture of the mouse hippocampus: Identification of gene loci with regional effects. Genes, Brain and Behavior, 2003,2:238-252

11. Chesler EJ, Wang J, Lu L, Qu Y, Manly KF, Williams RW: Genetic Correlates of gene expression in recombinant inbred strains: a relational model system to explore neurobehavioral phenotypes. Neuroinformatic 2003; 1(4): 343-357

12. Abiola O,Lu L,Zou F: The nature and identification of quantitative trait loci: a community's view. Nature Genetics 2003;4:911-916

13. Hsu HC, Zhang HG, Li L, Yi N, Yang PA, Wu Q, Zhou J, Sun S, Xu X, Yang X, Lu L, Van Zant G, Williams RW, Allison DB, Mountz JD: Age-related thymic involution in C57BL/6J X DBA/2J recombinant inbred mice maps to mouse chromosomes 9 and 10. Genes and Immunity, 2003, 4(6): 402-410

14. Seecharan DJ, Kulkarni AL, Lu L, Rosen GD, Williams RW: Genetic control of interconnected neuronal populations in the mouse primary visual system. Journal of Neuroscience, 2003, 23: 11178-11188

15. Churchill GA, Lu L, Zou F: The Collaborative Cross, a community resource for the genetic analysis of complex traits. Nature Genetics 2004, 36(11):1133-7

16. Williams RW, Bennett B, Lu L, Gu J, DeFries JC, Carosone-Link PJ, Rikke BA, Belknap JK and Johnson TE: Genetic Structure of the LXS Panel of Recombinant Inbred Mouse Strains: A Powerful Resource for Complex Trait Analysis. Mammalian Genome, 2004, 15(8):637-647

17. Peirce JL*, Lu L*, Gu J, Silver LM, Williams RW: A new set of BXD recombinant inbred lines from advanced intercross populations in mice. BMC Genetics 2004, 5(1):7; (co-first author)

18. Jablonski MM, Lu L, Wang XF, Chesler EJ, Carps E, Qi SH, Gu J, Williams RW: The ldis1 lens mutation in RIIIS/J mice maps to chromosome 8 near cadherin 1. Molecular Vision 2004, 10:577-87

19. Chesler EJ, Lu L, Wang J, Williams RW, Manly KF: WebQTL: Rapid Exploratory Analysis of Gene Expression and Genetic Networks for Brain and Behavior. Nature Neuroscience, 2004, 7(5): 485-486

20. Chesler EL*, Lu L*, Shou S, Qu Y, Gu J, Wang J, Hsu H, Mountz JD, Baldwin N, Langston MA, Hogenesch JB, Threadgill DW, Manly KF, Williams RW: Complex trait analysis of gene expression uncovers polygenic and pleiotropic networks that modulate nervous system function. Nature Genetics 2005, 37(3):233-42; (Co-first author)

21. Bystrykh L, Weersing E, Dontje B, Sutton S, Pletcher MT, Wiltshire T, Su AI, Vellenga E, Wang J, Manly KF, Lu L, Chesler EJ, Alberts R, Jansen RC, Williams RW, Cooke MP, de Haan G: Uncovering regulatory pathways that affect hematopoietic stem cell function using 'genetical genomics'. Nature Genetics 2005, 37(3):225-32

22. Mountz JD, Yang PA, Wu Q, Zhou J, Tousson A, Fitgerald A, Allen J, Wang X, Cartner S, Grizzle WE, Yi N, Lu L, Williams RW, and Hsu HC: Genetic segregation of spontaneous erosive arthritis and generalized autoimmune disease in BXD2 recombinant inbred strain of mice. Scandinavian Journal of Immunology 2005,61(2):128-38

23. Zou F, Gelfond J, Airey DC, Lu L, Manly KF, Williams RW, and Threadgill DW: Extending the power of quantitative trait locus analysis using recombinant inbred lines through recombinant inbred intercrosses (RIX): theoretical and empirical considerations. Genetics, 2005, 170(3): 1299-1311

24. Li HQ, Lu L, Manly KF, Wang J, Zhou M, Williams RW, Cui Y: Inferring gene transcriptional modulatory relations: a genetical genomics approach. Human Molecular Genetics, 2005, 14(9): 1119-1125

25. Tsaih, SW, Lu L, Airey DC, Williams RW, Churchill GA: Quantitative trait mapping in a diallel cross of recombinant inbred lines. Mammalian Genome, 2005, 16:344-355

26. Jablonski MM, Dalke C, Wang XF, Lu L, Manly K, Pretsch W, Pardue M, Rinchik, Williams RW, Goldowitz D, Graw J: An ENU-induced mutation in Rs1h causes disruption of retinal structure and function. Molecular Vision, 2005,11:569-81

27. Matthews DB, Bhave SV, Belknap JK, Brittingham C, Chesler EJ, Hitzemann RJ, Hoffmann PL, Lu L, McWeeney S, Miles MF, Tabakoff B, Williams RW: Complex Genetics of Interactions of Alcohol and CNS Function and Behavior. Alcohol Clin Exp Res, 2005 Sep;29(9):1706-1719

28. Bennett B, Carosone-Link PJ, Lu L, Chesler EJ, Johnson TE: Genetics of body weight in the LXS recombinant inbred mouse strains. Mammalian Genome, 2005 Oct 16(10):764-74

29. Vazquez-Chona FR, Khan AN, Chan CK, Moore AN, Dash PK, Rosario Hernandez R, Lu L, Chesler EJ, Manly KF, Williams RW, Geisert Jr EE: Genetic networks controlling retinal injury. Molecular Vision, 2005, 11:958-970

30. Li CX, Wei X, Lu L, Peirce JL, Williams RW, Waters RS: Genetic Analysis of Barrel Field Size in the First Somatosensory Area (SI) in Inbred and Recombinant Inbred Strains of Mice. Somatosensory and Motor Research, 2005, 22:141-150

31. Jablonski MM, Wang XF, Lu L, Miller DR, Rinchik EM, Williams RW, Goldowitz D: The Tennessee Mouse Genome Consortium: Identification of Ocular Mutants. Visual Neuroscience, 2005, 22(5):595-604

32. Kempermann G, Chesler EJ, Lu L, Lein E, Nathanson J, Williams RW, Gage FH: Natural variation and genetic covariance in adult hippocampal neurogenesis. Proc Natl Acad Sci USA, 2006, 103(3):780-5

33. Li HQ, Chen H, Bao L, Manly KF, Chesler EJ, Lu L, Wang J, Zhou M, Williams RW, Cui Y: Integrative Genetic Analysis of Transcription Modules: Towards Filling the Gap between Genetic Loci and Inherited Traits. Human Molecular Genetics, 2006,15(3):481-92

34. Bao L, Wei L. Peirce JL, Homayouni R, Li H, Zhou M, Chen H, Lu L, Williams RW, Pfeffer LM, Goldowitz D, Cui Y: Combining gene expression QTL mapping and phenotypic spectrum analysis to uncover gene regulatory relations. Mammalian Genome, 2006, 17(6):575-583

35. PeirceJL, Li H, WangJ, ManlyKF, Hitzemann RJ, BelknapJK, RosenGD, Sutter TR, Williams RW, Lu L: How replicable are mRNA expression QTL? Mammalian Genome, 2006, 17(6):643-656

36. Martin M, Dong H, Vallera D, Lee D, Lu L, Williams RW, Rosen GD, Cheverud J, Csernansky J: Independent quantitative trait loci influence ventral and dorsal hippocampal volume in recombinant inbred strains of mice. Genes, Brain and Behavior, 2006 Nov, 5:614–623

37. Mozhui K, Hamre KM, Holmes A, Lu L, Williams RW: Genetic and structural analysis of the basolateral amygdala complex in BXD recombinant inbred mice. Behavior Genetics, 2007, 37:223–243

38. Bao L, Zhou M, Ligang Wu, Lu L, Goldowitz D, Williams RW, Cui Y: PolymiRTS Database: linking polymorphisms in microRNA target sites with complex traits. Nucleic Acids Research, 2007 Jan;35(Database issue):D51-4

39. Bao L, Peirce JL, Lu L, Zhou M, Li H, Goldowitz D, Williams RW, Cui Y: An integrative genomics strategy for systematic characterization of genetic loci modulating phenotypes. Human Molecular Genetics, 2007, 16(11):1381-90

40. Gatti D, Maki A, Chesler EJ, Kosyk O, Kirova R, Lu L, Manly KF, Qu Y, Williams RW, Perkins A, Langston ME, Threadgill DW, Rusyn I: Genome-level analysis of genetic regulation of liver gene expression networks. Hepatology, 2007, 46(2):548-57

41. Dong H, Martin M, Colvin J, Ali Z, Borek J, Wang L, Lu L, Williams RW, Rosen GD, Csernansky JG, Cheverud J: Quantitative trait loci linked to thalamic and cortical gray matter volumes in BXD recombinant inbred mice: implications for the genetics of schizophrenia. Heredity, 2007, 99(1):1381-90

42. Miyairi I, Tatireddigari A, Madi OS, Rose LA, Belland RJ, Lu L, Williams RW, Byrne GI: The p47 GTPases Iigp2 and Irgb10 regulate innate immunity and inflammation to murine Chlamydial psittaci infection. Journal of Immunology 2007,179:1814-1824; PMID: 17641048

43. Aziz RK, Kansal R, Abdeltawab NF, Rowe SL, Su Y, Carrigan D, Nooh MM, Attia RR, Brannen C, Gardner LA, Lu L, Williams RW, Kotb M: Susceptibility to severe Streptococcal sepsis: use of a large set of isogenic mouse lines to study genetic and environmental factors. Genes and Immunity, 2007, 8(5):404-15

44. Vázquez-Chona FR, Lu L, Geisert EE: Genomic Loci Modulating the Retinal Transcriptome in Wound Healing. Gene Regulation and System Biology 2007:1 327–348

45. Ding M, Lu L, Toth LA: Microarray gene expression in lung and basal forebrain of uninfected and influenza-infected C57BL/6J and BALB/cByJ. Genes, Brain and Behavior, 2008, 7(2): 173–183

46. PeirceJL, BromanKW, Lu L, Williams RW: A simple method for combining QTL maps multiple crosses and experimental designs. Plos ONE 2007, 2(10):e1036

47. Jan T, Lu L, Li C, Williams RW, Waters RS: Genetic analysis of posterior medial barrel subfield (PMBSF) size in somatosensory cortex (SI) in recombinant inbred strains of mice. BMC Neuroscience 2008, 9:3 doi:10.1186/1471-2202-9-3

48. Abdeltawab NF, Aziz RK, Kansal R, Rowe SL, Su Y, Gardner L, Brannen C, Nooh MM, Attia RR, Abdelsamed HA, Taylor WL, Lu L, Williams RW, Kotb M: An unbiased systems genetics approach to mapping genetic loci modulating susceptibility to severe streptococcal sepsis. PLoS Pathogens 2008,4(4):e1000042. PMC2277464

49. Peirce JL, Broman KW, Lu L, Chesler EJ, Zhou G, Airey DC, Birmingham AE, Williams RW: Genome reshuffling for advanced intercross permutation (GRAIP): A permutation method for quantitative advanced intercross population analysis. PLoS One 2008, 3(4):e1977. PMC2295257

50. Lu L, Wei L, Peirce JL, Wang X, Zhou J, Homayouni R, Williams RW, Airey DC: Using gene expression databases for classical trait QTL candidate gene discovery in the BXD recombinant inbred genetic reference population: mouse forebrain weight. BMC Genomics. 2008 Sep 25;9(1):444. PMC2570693

51. Reiner DJ, Jan TA, Boughter JD Jr, Li CX, Lu L, Williams RW, Waters RS: Genetic Analysis of Tongue Size and Taste Papillae Number and Size in Recombinant Inbred Strains of Mice. Chem Senses. 2008 Oct;33(8):693-707. PMC2565774

52. Olsen C, Huang Y, Goodwin S, Ciobanu D, Lu L, Sutter T, Winder D: Microarray Analysis Reveals Distinctive Signaling Between the Bed Nucleus of the Stria Terminalis, Nucleus Accumbens, and Dorsal Striatum. Physiological Genomics 2008 Feb 19;32(3):283-98

53. Mozhui K, Ciobanu DC, Schikorski T, Wang X, Lu L, Williams RW: Dissection of a QTL hotspot on mouse distal chromosome 1 that modulates neurobehavioral phenotypes and gene expression. PLoS Genet. 2008 Nov;4(11):e1000260. Epub 2008 Nov 14. PMC2577893

54. Kotb M, Fathey N, Aziz R, Rowe S, Williams RW, Lu L: Unbiased forward genetics and systems biology approaches to understanding how gene-environment interactions work to predict susceptibility and outcomes of infections. Novartis Foundation Symposium. 2008;293:156-65; discussion 165-7, 181-3. PMID: 18972751

55. Williams RW, Lu L: integrative genetic analysis of alcohol dependence using the genenetwork web resources. Alcohol Research & Health, 2008 Vol. 31 (3): 275-277

56. Abdeltawab N, Kansal R,Rowe S, Gardner L, Brannen C, Nooh M, Mukundan S, Abdelsamed, HAttia R, Taylor W, Lu L, Williams RW and Kotb M: Bioinformatics analysis of immune response to group A streptococcal sepsis integrating quantitative trait loci mapping with genome-wide expression studies. BMC Bioinformatics 2008, 9(Suppl 7): P6.

57. Carneiro AM, Airey DC, Zhu C, Thompson B, Zhu C, Lu L, Chessler EJ, Erikson KM, Blakely RD: Functional Coding Variation in Recombinant Inbred Mouse Lines Reveals Multiple Serotonin Transporter-Associated Phenotypes. Proc Natl Acad Sci USA, 2009 vol.106 (5):2047-2052

58. Rosen GD, Pung CJ, Owens CB, Caplow J, Kim H, Mozhui K, Lu L, Williams RW: Genetic modulation of striatal volume by loci on Chrs 6 and 17 in BXD recombinant inbred mice. Genes Brain Behav. 2008 Jan 9. PMC2706028

59. Brigman JL, Mathur P, Lu L, Williams RW and Holmes A: Genetic relationship between anxiety-related and fear-related behaviors in BXD recombinant inbred mice. Behavioural Pharmacology 2009, Mar; 20(2):204-9. PMC2701299

60. Shen Q, Wang X, Chen Y, Xu L, Wang X, Lu L: Expression QTL and regulatory network analysis of microtubule-associated protein tau gene. Parkinsonism and Related Disorders 2009, Aug;15(7):525-31. PMID: 19233709

61. Dai J, Wang X, ChenY, WangX, Zhu J, Lu L: Expression QTL and Genetic Regulatory Network Analysis Reveals That Gabra2 is Involved in the Stress Response. Stress, 2009 Nov;12(6):499-506. PMID: 19212922

62. Gaglani SM, Lu L, Williams RW, Rosen GD: The genetic control of neocortex volume and covariation with neocortical gene expression in mice. BMC Neurosci. 2009 May 9;10:44. PMC2685397

63. Koutnikova H, Laakso M, Lu L, Combe R, Paananen J, Kuulasmaa T, Kuusisto J, Haring HU, Hansen T, Pedersen O, Smith U, Hanefeld M, Williams RW, Auwerx J: Identification of the UBP1 locus as a critical blood pressure determinant using a combination of mouse and human genetics. PLoS Genet. 2009 Aug;5(8):e1000591. Epub 2009 Aug 7. PMC2715105

64. Boon AC, deBeauchamp J, Hollmann A, Luke J, Kotb M, Rowe S, Finkelstein D, Neale G, Lu L, Williams RW, Webby RJ: Host genetic variation affects resistance to infection with a highly pathogenic H5N1 influenza A virus in mice. J Virol. 2009 Oct;83(20):10417-26. PMC2753106

65. Geisert EE*, Lu L*, Freeman-Anderson NE, Templeton JP, Nassr M, Wang X, Gu W, Jiao Y, Williams RW: Gene expression in the mouse eye: an online resource for genetics using 103 strains of mice. Mol Vis. 2009 Aug 31;15:1730-63, PMC2736153; (Co-first author)

66. Ciobanu DC, Lu L, Mozhui K, Wang X, Jagalur M, Morris JA, Taylor WL, Dietz K, Simon P, Williams RW: Detection, validation, and downstream analysis of allelic variation in gene expression. Genetics 2010 Jan;184(1):119-28. Epub 2009 Nov 2. PMID: 19884314, PMC2802080

67. Overall RW, Kempermann GK, Peirce J, Lu L, Goldowitz D, Gage FH, Goodwin S, Smit AB, Airey DC, Rosen GD, Leonard C. Schalkwyk LC, Sutter TR, Nowakowski RS, Whatley S and Williams RW: Genetics of the hippocampal transcriptome in mouse: a systematic survey and online neurogenomics resource. Frontiers in Neurogenomics (Neuroscience), 2009 Nov, 1:1-10, doi: 10.3389/neuro.15.003.2009. PMC2858614

68. Wang X, Chen Y, Wang XD, Lu L: Genetic regulatory network analysis for App based on genetical genomics approach. Experimental Aging Research, 2010 36: 79–93. PMID: 20054728

69. Wang JH, Li J, Wu Q,Yang PA, Pawar RD, Xie S, Timares L, Raman C, Chaplin DD, Lu L, Mountz JD, and Hsu HC: Marginal Zone Precursor B Cells as Cellular Agents for Type I IFN Promoted Antigen Transport in Autoimmunity. J Immunol. 2010 January 1; 184(1): 442–451. doi:10.4049/jimmunol.0900870

70. Mulligan MK, Rogers Jr. GL, Lu L, Langston MA, Williams RW: Genetic analysis of BDNF expression cliques and adult neurogenesis in the hippocampus. IEEE BSEC, 2010, 10.1109/BSEC.2010.5510847

71. Ziebarth JD, Cook MN, Li B, Williams RW, Lu L*, Cui Y*: Systems genetics analysis of molecular pathways underlying ethanol-induced behavioral phenotypes. IEEE BSEC, 2010, 10.1109/BSEC.2010.5510821, (Co-corresponding author)

72. Li Z, Mulligan MK, Wang X, Miles MF, Lu L, Williams RW: A mutation in Comt generates mRNA isoforms and causes widespread expression and behavioral differences among inbred mice. PLoS ONE 2010, Aug 17;5(8):e12181. PMID: 20808911, PMCID: PMC2923157

73. Lionikas A, Carlborg O, Lu L, Peirce JL, Williams RW, Yu F, Vogler GP, Mcclearn GE, and Blizard DA: Genomic Analysis of Variation in Hindlimb Musculature of Mice from the C57BL/6J and DBA/2J Lineage. Journal of Heredity, 2010 May-Jun;101(3):360-7. PMID: 20233743, PMCID: PMC2855676

74. Jablonski MM, Freeman NE, Orr WE, Templeton JP, Lu L, Williams RW, Geisert EE: Pathways regulating glutamate levels in retinal Muller cells. Neurochem Res 2011 Sep. 36:594-603, DOI 10.1007/s11064-010-0277-1, PMID: 20882406

75. Poon A, Li Z, Wolfe C, Lu L, Williams RW, Hayes NL. Nowakowski RS, Goldowitz D: Identification of a Chr 11 quantitative trait locus that modulates proliferation in the rostral migratory stream of the adult mouse brain. European Journal of Neuroscience, 2010 Aug;32(4):523-37. PMID: 20718853

76. Lu H, Chen H, Chen H, Lu L*, Guan H*: Genetic regulatory network analysis for Myoc based on genetical genomics approach. Biomedical Engineering and Informatics (BMEI), 2010, 10.1109/BMEI.2010.5639531, (Co-corresponding author)

77. Reinius B, Shi C, Hengshuo L, Sandhu KS, Radomska KJ, Rosen GD, Lu L, Kullander K, Williams RW and Jazin E: Female-biased expression of long non-coding RNAs in domains that escape X-inactivation in mouse. BMC Genomics 2010, 11:614, PMID: 21047393; PMCID: PMC3091755

78. Gatti DM, Zhao N, Chesler EJ, Bradford BU, Shabalin A, Yordanova R, Lu L, and Rusyn I: Sex-specific gene expression in BXD mouse liver. Physiol Genomics, 2010 vol.42, p.456-468; PMCID: PMC2929887

79. Wang X, Agarwala R, Capra JA, Chen Z, Church DM, Ciobanu DC, Li Z, Lu L, Mozhui K, Megan K Mulligan MK, Nelson SF, Pollard KS, Taylor WL, Thomason DB, Williams RW: High-throughput sequencing of the DBA/2J mouse genome. BMC Bioinformatics 2010, 11(Suppl 4):O7

80. McLachlan SM, Lu L, Aliesky HA, Williams RW, and Basil Rapoport B: Distinct Genetic Signatures for Variability in Total and Free Serum Thyroxine Levels in Four Sets of Recombinant Inbred Mice. Endocrinology, 2011 Mar;152(3):1172-9. Epub 2011 Jan 5, PMCID: PMC3040052

81. Porcu P, O'Buckley Tk, Song SC, Harenza JL, Lu L, Wang X, Williams RW, Miles MF, Morrow AL: Genetic analysis of the neurosteroid deoxycorticosterone and its relation to alcohol phenotypes: identification of QTLs and downstream gene regulation. PLoS One, 2011; 6(6):10.1371; PMCID: PMC3128548

82. Yin L, Lu L, Prasad K, Richfield EK, Unger EL, Xu J, Jones BC: Genetic-based, differential susceptibility to paraquat neurotoxicity in mice. Neurotoxicology and Teratology, 2011, doi:10.1016/j.ntt.2011.02.012

83. Lu H, Wang X, Pullen M, Guan H, Chen H, Sahu S, Zhang B, Chen H, Williams RW, Geisert EE, Lu L*, Jablonski MM*: Genetic Dissection of the Gpnmb Network in the Eye. Invest Ophthalmol Vis Sci. 2011 Mar 11. PMCID: PMC3175941; (Co-corresponding author)

84. Alberts R, Lu L, Williams RW, Schughart K: Genome-wide analysis of the mouse lung transcriptome reveals novel molecular gene interaction networks and cell-specific expression signatures. Respiratory Research, 2011 May 2;12:61. Erratum in: Respir Res. 2012;13(1):5; PMCID: PMC3105947

85. Yan L, Zhou X, Lu L, Centeno A, Kuan L, Hawrylycz M, Larimer M, Rosen GD, Williams RW: Global exploratory analysis of massive neuroimaging collections using Microsoft Silverlight PivotViewer. IEEE BSEC, 2011, 10.1109/BSEC.2011.5872323

86. Gatti DM, Lu L, Williams RW, Sun W, Wright FA, Threadgill DW, Rusyn I: MicroRNA expression in the livers of inbred mice. Mutation Research: Fundam. Mol. Mech. Mutagen, 2011 Sep 1;714(1-2):126-33. Epub 2011 May 14; PMCID: PMC3166582

87. Freeman NE, Templeton JP, Orr WE, Lu L, Williams RW, Geisert EE: Genetic networks in the mouse retina: Growth Associated Protein 43 and Phosphate Tensin Homology network. Molecular Vision, 2011, 17:1355-1372; PMCID: PMC3108897

88. Mozhui K, Wang X, Chen J, Mulligan MK, Li Z, Ingles J, Chen X, Lu L, Williams RW: Genetic regulation of Nrnx1 expression: an integrative cross-species analysis of schizophrenia candidate genes. Translational Psychiatry, 2011 1:e25; doi:10.1038/tp.2011.24.

89. Whitney IE, Raven MA, Lu L, Williams RW, Reese BE: A QTL on chromosome 10 modulates cone photoreceptor number in the mouse retina. Investigative Ophthalmology and Visual Science, 2011 May 16;52(6):3228-36, PMCID: PMC3109025, IF 3.58

90. Lu H, Li L, Watson ER, Williams RW, Geisert EE, Jablonski MM, and Lu L: Complex interactions of Tyrp1 in the eye. Mol Vis, 2011, 17:2455-2468; PMCID: PMC3185026

91. Lu H, Guan H, Chen H, Lu L: Genetic regulatory network analysis for Rpe65 in the eye of BXD mice. Advanced Materials Research Vols. 282-283 (2011) pp 248-252

92. Chen Y, Zhao Y, Wang X, Li Y, Ke K, Yue J, Hori R, Lu L: Preliminary study of Alzheimer's disease related genes by using genetical genomics approach. Biomedical Engineering and Informatics (BMEI), 2011, 978-1-4244-9350-0/11

93. Jiao Y, Lu L, Williams RW, Smeyne RJ: Genetic dissection of strain dependent paraquat-induced neurodegeneration in the substantia nigra pars compacta. PLoS One. 2012;7(1):e29447. Epub 2012 Jan 24, PMCID: PMC3265472

94. Ziebarth JD, Cook MN, Wang X, Williams RW, Lu L*, and Cui Y*: Treatment- and population-dependent activity patterns of behavioral and expression QTLs. PLoS One. 2012;7(2):e31805. Epub 2012 Feb 16.. PMCID: PMC3281015, (Co-corresponding author)

95. Wang X, Mozhui K, Li Z, Mulligan MK, Ingels JF, Hori RT, Chen H, Cook MN, Williams RW, Lu L: A promoter polymorphism in the Per3 gene is associated with alcohol and stress response. Translational Psychiatry, 2012 Jan 31;2:e73. doi: 10.1038/tp.2011.71. , (New Journal, IF is not available, but is expected to be 7 and above), PMCID: PMC3309544

96. Mozhui K, Lu L, Armstrong WE, Williams RW: Sex-specific modulation of gene expression networks in murine hypothalamus. Front Neurosci. 2012, 6:63. PMID: 22593731, PMCID: PMC3350311

97. Hong Lu, Huaijin Guan, Hui Chen, Lu Lu: Expression QTL and genetic regulatory network analysis of Col11a1. Biomedical Engineering and Informatics (BMEI), 2012, 978-1-4673-1182-3/10

98. Rosen GD, Azoulay NA, Griffin EG, Newbury A, Koganti L, Fujisaki N, Takahashi E, Grant PE, Truong DT, Fitch RH, Lu L, Williams RW: Bilateral Subcortical Heterotopia with Partial Callosal Agenesis in a Mouse Mutant. Cereb Cortex. 2012 Mar 27, PMID: 22455839

99. Miyairi I, Ziebarth J, Laxton JD, Wang X, Rooijen NV, Williams RW, Lu L, Byrne GI, Cui Y: Host Genetics and Chlamydia Disease: Prediction and Validation of Disease Severity Mechanisms. PLoS ONE, 2012;7(3):e33781. Epub 2012 Mar 16, PMCID: PMC3306297

100. Jellen LC, Unger EL, Lu L, Williams RW, Rousseau S, Wang X, Earley CJ, Allen RP, Miles MF, Jones BC: Systems Genetic Analysis of the Effects of Iron Deficiency in Mouse Brain. Neurogenetics. 2012 Mar 29, 13:147–157, PMID: 22457016

101. McKnite AM, Perez-Munoz ME, Lu L, Williams EG, Brewer S, Andreux P, Bastiaansen JWM, Wang X, Kachman SD, Auwerx J, Williams RW, Benson AK, Peterson DA, Ciobanu DC: Murine Gut Microbiota is Defined by Host Genetics and Modulates Variation of Metabolic Traits. PLoS One, 2012 June, Vol 7 (6): e39191

102. Mulligan MK, Wang X, Adler AL, Mozhui K, Lu L, William RWs: Complex Control of GABA(A) Receptor Subunit mRNA Expression: Variation, Covariation, and Genetic Regulation. PLoS ONE, 2012 April, Vol 7 (4): e34586, PMCID: PMC3323555

103. Zhu ZH, Zhang CH, Wang XS, Cook MN, Williams RW, Lu L* and ZHU J*: Dissecting anxiety-related QTLs in mice by univariate and multivariate mapping. Chinese Science Bulletin, 2012, 27:1~6, (Co-corresponding author),

104. Nedelko T, Kollmus H, Klawonn F, Spijker S, Lu L, Heszmann M, Alberts R, Williams RW, Schughart K (2012) Distinct gene loci control the host response to influenza H1N1 virus infection in a time-dependent manner. BMC Genomics, 2012, 13:411, doi:10.1186/1471-2164-13-411

105. Hager R*, Lu L*, Glenn D. Rosen GD, Williams RW: Genetic architecture supports mosaic brain evolution and independent brain–body size regulation. Nature Communications, 2012, 3:1079 | DOI: 10.1038/ncomms2086, (Co-first author)

106. Heck DH and Lu L: The Social Life of Neurons: Synaptic Communication Deficits as a Common Denominator of Autism, Schizophrenia, and Other Cognitive Disorders. BIOL PSYCHIATRY 2012;72:173–174, PMCID: PMC3417140

107. Boughter Jr JD, Mulligan MK, St. John SJ, Tokita K, Lu L, Heck D, Williams RW: Genetic control of a central pattern generator: rhythmic oromotor movement in mice is controlled by a major locus near Atp1a2. PLoS ONE, 2012 7(5):e38169. 4.09 Impact Factor., PMCID: PMC3364982

108. Wang LS, Jiao Y, Huang Y, Liu XY, Gibson G, Bennett B, Hamre KM, Li DW, Zhao HY, Gelernter J, Kranzler HR, Farrer LA, Lu L, Wang YJ, Gu WK: Critical evaluation of transcription factor Atf2 as a candidate modulator of alcohol preference in mouse and human populations.. Genet Mol Res. 2013 Nov 26;12(4):5992-6005. doi: 10.4238/2013

109. Yan Jiao, Hong Chen, Jian Yan, lishi Wang, yue Huang, Xiaoyun, Liu, Robert Williams, Lu Lu, YongJun Wang, Weikuan Gu: Genome-wide gene expression profiles in antioxidant pathways and their potential sex differences and connections to vitamin C in mice. International Journal of Molecular Sciences 2013, 14, 10042-10062; doi:10.3390/ijms140510042

110. Swaminathan S, Lu H, Williams RW, Lu L*, and Jablonski MM*: Genetic modulation of the iris transillumination defect: a systems genetics analysis using the expanded family of BXD glaucoma strains. Pigment Cell Melanoma Res. 2013, Jul;26(4):487-98 (PMCID: PMC3752936 ) (Co-corresponding author)

111. Mulligan MK, DuBose C, Yue J, Miles MF, Lu L*, Hamre KM*: Expression, Covariation, And Genetic Regulation Of miRNA Biogenesis Genes In Brain Supports Their Role In Addiction, Psychiatric Disorders, And Disease. Frontiers in Statistical Genetics and Methodology, 2013 Jul 5;4:126. doi: 10.3389/fgene.2013.00126. eCollection 2013 (PMCID: PMC3701868 ) (Co-corresponding author)

112. Jones BC, Miller DB, O'Callaghan JP, Lu L, Unger EL, Alam G, Williams R W: Systems analysis of genetic variation in MPTP neurotoxicity in mice. Neurotoxicology, 37:26-34, 2013.

113. Jellen LC, Lu L, Wang X, Unger EU, Earley CJ, Allen RP, Williams RW, Jones BC: Iron deficiency alters expression of dopamine-related genes in the ventral midbrain in mice. Neuroscience, 2013, 252:13–23

114. Skobowiat C, Nejati R, Lu L, Williams RW, and Slominski A: Genetic variation of the cutaneous HPA axis: An analysis of UVB-induced differential responses. GENE 2013, 530:1–7

115. Guo Y, Tian P, Yang C, Li M, Sims M, Lu L, Zhang Z, Li H, Pfeffer LM, Yue J: Silencing the double-stranded RNA binding protein DGCR8 inhibits ovarian cancer cell proliferation, migration and invasion. Pharmaceutical Research, 2013, DOI 10.1007/s11095-013-1219-9

116. Ye R, Carneiro AM, Airey D, Sanders-Bush E, Williams RW, Lu, L, Wang J, Zhang B, and Blakely RD: Evaluation of Heritable Determinants of Blood and Brain Serotonin Homeostasis Using Recombinant Inbred Mice. Genes, Brain and Behavior, 2014, 13: 247–260

117. Ye R, Carneiro AM, Han Q, Airey D, Sanders-Bush E, Zhang B, Lu L, Williams RW, and Blakely RD: Quantitative trait loci mapping and gene network analysis implicate protocadherin-15 as a determinant of brain serotonin transporter expression. Genes, Brain and Behavior, 2014, 13: 261–275

118. Jones BC, Huang X, Mailman RB, Lu L, Williams RW: The Perplexing Paradox of Paraquat: the Case for Host-Based Susceptibility and Postulated Neurodegenerative Effects. J BIOCHEM MOLECULAR TOXICOLOGY, 2014, February 18, 14:2

119. Wang L, Lu W, Zhang L, Huang Y, Scheib R, Liu X, Myers L, Lu L, Farber CR, Liu G, Wang CY, Deng H, Williams RW, Wang Y, Gu W, Jiao Y. Trps1 differentially modulates the bone mineral density between male and female mice and its polymorphism associates with BMD differently between women and men. PLoS One. 2014 Jan 8;9(1):e84485. doi: 10.1371/journal.pone.0084485. eCollection 2014.

120. Pandey AK, Lu L, Wang X, Homayouni R, Williams RW: Functionally enigmatic genes: a case study of the brain ignorome. PLoS One. 2014 Feb 11;9(2):e88889. doi: 10.1371/journal.pone.0088889. eCollection 2014.

121. Ito J, Roy S, Liu Y, Cao Y, Fletcher M, Lu L, Boughter JD, Grun S, Heck DH: Whisker barrel cortex delta oscillations and gamma power in the awake mouse are linked to respiration. Nat Communication. 2014 Apr 1;5:3572. doi: 10.1038/ncomms4572.

122. Keeley PW, Zhou C, Lu L, Williams RW, Melmed S, Reese BE: Pituitary Tumor Transforming Gene 1 Regulates the Spacing of Retinal Neurons. PNAS, 2014, June 24, V111(25): 9295~9300

123. Ashbrook GD, Williams RW, Lu L, Stein LJ, Hibar PD, Nichols ET, Medland ES, Thompson MP, Hager R: Joint genetic analysis of hippocampal size in mouse and human identifies a novel gene linked to neurodegenerative disease. BMC Genomics, 2014, 15:850, DOI: 10.1186/1471-2164-15-850, IF 4.04

124. Huang Y, Zhu X, Wang L, Liu X, Lu L, Gu W, Jiao Y: Genome wide analysis of sex difference in gene expression profiles of bone formations using sfx mice and BXD RI strains. Scientific World Journal 2014, 2014:584910. doi: 10.1155/2014/584910. Epub 2014 Jul 14. PMCID: PMC4123512

125. Jones BC, O'Callaghan JP, Lu L, Williams RW, Alam G, Miller DB: Genetic correlational analysis reveals no association between MPP+ and the severity of striatal dopaminergic damage following MPTP treatment in BXD mouse strains. Neurotoxicol Teratol. 2014 Sep-Oct;45:91-2. doi: 10.1016/j.ntt.2014.08.005. Epub 2014 Sep 2. PMID: 25192776

126. Dan Goldowitz, Alexandre André Lussier, Julia K Boyle, kaelen Wong, Scott Lemar Lattimer, Candis DuBose, Lu Lu, Michael S Kobor, Kristin Hamre: Molecular pathways underpinning ethanol-induced neurodegeneration. Frontiers in Genetics 2014, Front Genet. 2014; 5: 203. PMCID: PMC4097813

127. Hibar DP, Stein JL, Renteria ME, Lu L, Thompson PM, Medland SE: Common genetic variants influence human subcortical brain structures. Nature 2015, doi:10.1038/nature14101

128. Zhang Y, Huang J, Jiao Y, David V, Kocak M, Roan E, Di'Angelo D, Lu L, Hasty KA, Gu W: Bone Morphology in 46 BXD Recombinant Inbred Strains and Femur-Tibia Correlation. Scientific World Journal. 2015;2015:728278. doi: 10.1155/2015/728278, PMCID: PMC4355808

129. XueYQ, Li J, Yan L, Lu Lu, Liao F: Genetic variability to diet-induced hippocampal dysfunction in BXD recombinant inbred (RI) mouse strains. Behavioural Brain Research 2015, 292:83~94

130. David G Ashbrook, Robert W Williams, Lu Lu, Reinmar Hager: A cross-species genetic analysis identifies candidate genes for mouse anxiety and human bipolar disorder. Frontiers in Behavioral Neuroscience, 2015 in press

131. Dr. Stacey: A translational systems biology approach identifies a functionally related module of accumbal genes involved in the regulation of reward processing and binge drinking in males. Journal of Psychiatry and Neuroscience, 2015 submit

Book Chapters

1. Hsu HC, Lu L, Yi N, Zant GV, Williams RW, Mountz JD: Quantitative Trait Loci (QTL) Mapping in Aging Systems for METHODS IN MOLECULAR BIOLOGY (Biological Aging: Methods and Protocols), Humana Press, Totowa, New Jersey, 2007, 371:321-348, DOI: 10.1007/978-1-59745-361-5_23

2. Lu L, Mulligan MK, and Heck D: Micro RNAs in neurodegenerative diseases in miRNA and Human Disease, published by Research Signpost, 2013.

3. Cook MN and Lu L: Big little issues: The role of miRNAs in stress and related disorders in miRNA and Human Disease, published by Research Signpost, 2013.

4. Yue J, Lu L, Chen Z, Tian P, Fan P, Guo Y, Li C, Gu W, Pfeffer L: microRNA and applications in miRNA and Human Disease, published by Research Signpost, 2013.

5. DuBose CS , Mulligan MK, Rooney RJ, Patel DH, Lu L and Hamre K: MicroRNAs, drugs of abuse, addiction, and alcoholism in miRNA and Human Disease, published by Research Signpost, 2013.

6. Lu H, Lu L: Chapter 404: Genetic Dissection of Pax6 through GeneNetwork in Frontier and Future Development of Information Technology in Medicine and Education, published by Springer Science, Business Media Dordrecht, 2014

Book:

1. Junming Yue and Lu Lu editors: Micro RNAs in neurodegenerative diseases published by Research Signpost, 2013 ISBN: 978-81-308-0503-0

Meeting Abstracts

1. Lu L, Xu HJ, Wu YM, Tian ML: Effects of laminin, gangliside GM1, and 1-Methyl-4-phonyl-1,2,3,6-tetrahydropyridine (MPTP) on growth and development of mesencephalic dopaminergic neurons in vitro. The 2^nd International Conference on Anatomical Sciences, Beijing China, October 12-15,1992

2. Wu YM, Lu L, Xu HJ, Tian ML: Effects of laminin on growth and development of mesencephalic dopaminergic neurons in vitro and in vivo. The 2^nd International Conference on Anatomical Sciences, Beijing, China, October 12-15, 1992

3. Lu L, Cao Z, Gu J, Ding F, Gu XS: Expression of the nerve growth factor gene in submandibular gland, testis and bone marrow. The 10^th International Congress on Histochemistry and Cytochemistry, Kyoto, Japan, August 18-23, 1996

4. Lu L, Airey DC, Gillissen E, Zhou GM, Williams RW: New murine hippocampus-specific QTL maps to distal Chr 1. The 13^th International Mouse Genome Conference. Philadelphia, USA, October 31-November 3, 1999

5. Airey DC, Lu L, Strom R, Gillissen E, Zhou GM, Williams RW: Cerebellum-specific QTLs in the mouse brain. The 13^th International Mouse Genome Conference, Philadelphia, USA, October 31-November 3, 1999

6. Lu L, Airey DC, Williams RW: Complex trait analysis of the mouse hippocampus. The 30^th Neuroscience Meeting, New Orleans, USA, November 4-9, 2000

7. Airey DC, Lu L, Williams RW: Gene loci for mouse cerebellum and internal granule layer size. The 30^th Neuroscience Meeting, New Orleans, USA, November 4-9, 2000

8. Williams RW, Kulkarni A, L Jones, Zhou GM, Airey DC, Lu L: Growth of the olfactory bulbs is modulated by QTLs on chromosomes 4,6,11 and 17. The 30^th Neuroscience Meeting, New Orleans, USA, November 4-9, 2000

9. Ding F, Cao Z, Lu L, Gu XS: Effects of lead exposure on transcription of nerve growth factor mRNA and cell growth of the submandibular gland of mice. The 30^th Neuroscience Meeting, New Orleans, USA, November 4-9, 2000

10. Rosen GD, Williams AG, Capra JA, Connolly MT, Cruz B, Lu L, Airey DC, Kulkarni A, Williams RW: The mouse brain library. The 14^th International Mouse Genome Conference, Narita, Japan, November 6-10, 2000

11. Williams RW, Threadgill DW, Airey DC, Gu J, Lu L: RIX Mapping: A demonstration using CXB RIX hybrids to map QTLs modulating brain weight in mice. The 31^th Neuroscience Meeting, San Diego, USA, November 10-15, 2001.

12. Threadgill DW, Airey DC, Lu L, Manly K, Williams RW: Recombinant inbred intercross mapping: a new approach to extend the power of existing mouse resources. The 15^th International Mouse Genome Conference, Edinburgh, Scotland, October 21-24, 2001.

13. Shou S, Lu L, Williams RW: Transcriptome chromosome maps: a novel resource for complex trait analysis of the mouse CNS. The 4^th Annual Meeting of the International Behavioural and Neural Genetics Society, San Diego, USA, November 8-10, 2001

14. Williams RW, Threadgill DW, Manly KF, Rosen GD, Shou S, Airey DC, Gu J, Lu L: Integrated complex trait analysis of brain and behavior in mouse: near-term prospects for high-resolution QTL mapping using large RI and RIX sets. The 4^th Annual Meeting of the International Behavioural and Neural Genetics Society, San Diego, USA, November 8-10, 2001

15. Lu L, Airey DC, Rosen GD, Williams RW: Genetic dissection of the mouse hippocampus: Mapping quantitative trait loci with selective and regional effects. International conference on neuroregeneration (ICN), Nantong, China, September 21-24, 2001

16. Williams RW, Lu L, Wang XF, Qi S, Gu J, Jablonski MM: Mapping and initial characterization of a spontaneous mutation affecting lens development in RIIIS/J inbred mice. The ARVO 2002 Annual Meeting, Ft Lauderdale, Florida, USA, May 4 - 9, 2002

17. Watson R, Koratkar R, Lu L, Gu J, Finegan AA, Margan JL, Guz J, Williams RW, Siracusa LD: Expansion of the BXH RI series: derivation and characterization of three new BXH recombinant inbred lines and one new BXH recombinant congenic line. Abst Amer Assoc Cancer Res 2002.

18. PeirceJL, Lu L, Zhou G, SilverLM, and WilliamsRW: Generation and Characterization of Highly Recombinant Inbred Lines from an Advanced Intercross. 1^st Annual Complex Trait Consortium (CTC) Meeting, Memphis, USA, May 15-17, 2002.

19. HsuHC, Huang-Ge Zhang HG, Li L, Mullinax C, Lu L, ZantGV, WilliamsRW, Allison DB, Mountz JD: Age-related Thymic Involution in C57BL/6J X DBA/2J Recombinant Inbred Mice Fits A Negative Exponential Regression Model and Maps to Mouse Chromosome 9. 1^st Annual Complex Trait Consortium (CTC) Meeting, Memphis, USA, May 15-17, 2002.

20. Lu L, Gu J, Qi SH, Airey DC, Rosen GD, Peirce J, Robert W. Williams RW, Zhou G: Analysis of a tenth generation advanced intercross and a new set of ~45 derivative BXD recombinant inbred strains. 1^st Annual Complex Trait Consortium (CTC) Meeting, Memphis, USA, May 15-17, 2002.

21. Threadgill D, Airey DC, Lu L, Manly KF, Williams RW: Genetic control of stochastic variation revealed by recombinant inbred intercross (RIX) mapping. 1^st Annual Complex Trait Consortium (CTC) Meeting, Memphis, USA, May 15-17, 2002.

22. Williams RW, Shou S, Lu L, Qu Y, Wang J, Manly K, Chesler E, Hsu HC, Mountz J, Threadgill D: Genomic Analysis of Transcriptional Networks: Combining Microarrays with Complex Trait Analysis. 1^st Annual Complex Trait Consortium (CTC) Meeting, Memphis, USA, May 15-17, 2002.

23. Lu L, Shou S, Qu YH, Manly K, Chesler E, Hsu HC, Mountz J, Threadgill D, Williams RW: Genomic Analysis of Transcriptional Networks: Combining Microarrays with Complex Trait Analysis. 2002 Southeast Regional Meeting of the Society for Developmental Biology, Gatlinburg, Tennessee, May 29-31,2002

24. Shou S, Lu L, Qu Y, Jensen P, Williams RW (2002) High transcriptional diversity and complexity among mouse brain regions. The 32^th Neuroscience Meeting, Orlando, USA, November 2-7 2002.

25. Williams RW, Shou S, Qu YH,Chesler E, Manly K, Wang J, Hsu HC, Mountz J, Threadgill D, Lu L: Massively parallel mapping of transcriptional networks. The 32^th Neuroscience Meeting, Orlando, USA, November 2-7 2002.

26. Tong Y, Deaton J, Lu L, Williams RW, Goldowitz D: Mapping of the hippocampal lamination defect gene, HLD, in the mouse. The 32^th Neuroscience Meeting, Orlando, USA, November 2-7 2002.

27. Lu L, Airey DC, Gu J, Zhou GM, Williams RW; Genetic architecture of the mouse hippocampus: Confirmation of gene loci with advanced intercross progeny. The 32^th Neuroscience Meeting, Orlando, USA, November 2-7 2002.

28. Smeyne RJ, Tharp R, Smeyne M, Lu L, Williams RW: Identification of quantitative trait loci for susceptibility to MPTP in an animal model of Parkinsons disease. The 32^th Neuroscience Meeting, Orlando, USA, November 2-7 2002.

29. Chesler EJ, Shou S, Qu Y, Yang X, Lu L, Williams RW: Microarray analysis of sex differences in the mouse CNS transcriptome. The 32^th Neuroscience Meeting, Orlando, USA, November 2-7 2002.

30. Jabblonski MM, Wang XF, Lu L, Goldowitz D, Williams RW, Tennessee Mouse Genome Consortium: Regional mutagenesis of the mouse genome: Ocular phenotypes. The 32^th Neuroscience Meeting, Orlando, USA, November 2-7 2002.

31. Williams RW, Manly KF, Shou S, Chesler EJ, Hsu HC, Mountz J, Threadgill DW, Lu L: Massively parallel complex trait analysis of transcriptional activity in mouse brain. The 16^th International Mouse Genome Conference, San Antonio, Texas, November 17-20, 2002.

32. Lu L, Gu J, Threadgill D, Williams R: Complex trait analysis of mice hippocampus using CXB RIX mapping method. The 16^th International Mouse Genome Conference, San Antonio, Texas, November 17-20, 2002.

33. Manly KF, Wang J, Shou S. Qu Y, Chesler E, Lu L, Hsu HC, Mountz JD, Threadgill D, Williams RW (2002) QTL mapping with microarray expression data. The 16^th International Mouse Genome Conference, San Antonio, Texas, November 17-20, 2002.

34. Williams RW, Lu L, Qu YH, Wang JT, Chesler EJ, Hsu HC, Mountz JD, Threadgill DW, Manly KF: Brain Transcriptional Control Networks. Fourteenth Annual Spring Brain Conference, Radisson Poco Diablo Resort in Sedona, Arizona, USA, March 12-15, 2003.

35. Geisert EE, Vazquez-Chona F, Lu L, Chesler EJ, Williams RW: The control of gene expression following injury in the rat retina: QTL and PCA. The ARVO 2003 Annual Meeting, Ft Lauderdale, Florida, USA, May 4 - 9, 2003.

36. Williams RW, Xu JL, Zhai HT, Lu L: Complex trait analysis of mouse retinal horizontal cell number. The ARVO 2003 Annual Meeting, Ft Lauderdale, Florida, USA, May 4 - 9, 2003.

37. Jablonski MM, Wang XF, Lu L, Pardue M, Iannaccone A, Goldowitz D, William RW: Regional Mutagenesis of the Mouse Genome: An Update of Ocular Phenotypes. The ARVO 2003 Annual Meeting, Ft Lauderdale, Florida, USA, May 4 - 9, 2003.

38. Chesler EJ, Wang JT, Lu L, Peirce JL, Manly KF, Williams RW: Web-based QTL mapping and genetic correlation analysis of gene expression and alcohol-related traits in BXD strains. Research Society for Alcoholism 26^th Annual meeting, Ft Lauderdale, Florida, USA, June 21-25, 2003.

39. De Koning DJ, Carlborg O, Williams RW, Lu L, Haley C (2003) Epistatic QTL for gene expression in mice: potential for BXD expression data. The 2nd Annual Complex Trait Consortium (CTC) Meeting, Oxford, UK, July 1-3, 2003.

40. Chesler EJ, Wang JT, Lu L, Qu, Y, Manly K, 1Williams RW: Genetic correlations and associative networks for CNS transcript abundance and neurobehavioral phenotypes in a recombinant inbred mapping panel. The 2nd Annual Complex Trait Consortium (CTC) Meeting, Oxford, UK, July 1-3, 2003

41. Chesler, E.J., Wang, J., Lu, L., Peirce, J.L., Qu, Y., Manly, K.F., Williams, R.W., (2003) Web-based QTL mapping and genetic correlation analysis of gene expression and alcohol-related traits in BXD strains. Alc. Clin. Exp Res. Supplement 27(5):125A.

42. Lu L, Chesler EJ, Chen H, Li Y, Cui Y, Sharp BM, Wang JT, Manly K, Williams RW: Genomic Analysis of Gene Interaction In Mice Forebrain. The 2nd Annual Complex Trait Consortium (CTC) Meeting, Oxford, UK, July 1-3, 2003

43. Osadchuk AV, Airey DC, Lu L, Threadgill DW, Williams RW: A novel approach to genetically dissect complex quantitative traits using a diallel cross of recombinant inbred strains. The 2nd Annual Complex Trait Consortium (CTC) Meeting, Oxford, UK, July 1-3, 2003

44. Lu. L, Cui Y, Chesler EJ, Chen H, Li Y, Sharp BM, Williams RW: Genetic dissection of transcriptional regulatory networks in mouse forebrain. The 33^th Neuroscience Meeting, New Orleans, USA, November 8-12 2003.

45. Chesler EJ, Wang JT, Lu L, Qu, Y, Manly K, 1Williams RW: Gene expression associative networks and genetic correlations of CNS transcript abundance with neuro-behavioral phenotypes in a recombinant inbred mapping panel. The 33^th Neuroscience Meeting, New Orleans, USA, November 8-12 2003.

46. Kempermann G, Chesler EJ, Lu. L, Williams RW, Gage FG: Search for key gene loci associated with the baseline regulation of adult hippocampal neurogenesis. The 33^th Neuroscience Meeting, New Orleans, USA, November 8-12 2003.

47. Matthews DB, Lu L, Chesler EJ, Mittleman G, Williams RW: Identification of two QTLs on chromosome 16 modulating vocalization to mild foot shock in mice. The 33^th Neuroscience Meeting, New Orleans, USA, November 8-12 2003.

48. Boughter JD, Jr., John SJ, Williams RW, and Lu L: Genetic Control of Lick Rate in Mice. The 26^th Annual Meeting of the Association for Chemoreception Sciences. Sarasota, FL, USA, April 21-25, 2004.

49. Chesler EJ, Wang JT, Lu L, Qu, Y, Manly K, 1Williams RW: WebQTL: A resource for analysis of gene expression variation and the genetic dissection of alcohol related phenotypes. The 27^th Annual Scientific Meeting of the Research Society on Alcoholism, Westin Bayshore Resort and Marina Vancouver, Canada, June 26-30, 2004.

50. Osadchuk AV, Airey DC, Lu L, Threadgill DW, Williams RW: A new look at the genetic dissection of complex quantitative traits in the extended RIX diallel cross: multilocus approach. The 3rd Annual Complex Trait Consortium (CTC) Meeting, Bar Harbor, ME, USA July 6-9, 2004

51. Chesler EJ, Baldwin NE, Zhang B, Kirov S, Wang J, Lu L, Snoddy JR, Langston MA, Manly KF, Williams RW: Genetic analysis of gene expression in mouse CNS reveals major pleiotropic and polygenic control of synaptic machinery. The 18th International Mouse Genome Conference, Seattle, USA, October 18-21, 2004

52. Jablonski MM, Wang XF, Lu L, Williams RW, Goldowitz D: The Tennessee Mouse Genome Consortium: An update of ocular phenotypes. The 34^th Neuroscience Meeting, San Diego, USA, October 23-27, 2004

53. Chesler EJ, Lu L, Langston MA, Manly KF, Williams RW: Transcriptome - QTL analysis of correlated CNS transcripts using WEBQTL reveals major genetic variation in synaptic vesicle related gene expression. The 34^th Neuroscience Meeting, San Diego, USA, October 23-27, 2004

54. Geisert EE, Khan AN, Chesler EJ, Manly KF, Williams RW, Lu L, Vazquez-Chona F: Master regulators of glia cell reactivity. The 34^th Neuroscience Meeting, San Diego, USA, October 23-27, 2004

55. Jablonski MM, Wang X, Lu L, Manly K, Rinchik E, Pardue M, Williams RW, Goldowtiz D: Characterization of a new mutant mouse model with an aberrant retinal phenotype: 44TNJ (tmgc1) from the Tennessee Mouse Genome Consortium. The ARVO 2005 Annual Meeting, Ft Lauderdale, Florida, USA, May 1 - 5, 2005.

56. HsuHC, Lu L, YiN, WilliamsRW, and MountzJD: Production of autoantibodies and urinary proteins in autoimmune BXD2 mice mapped to mouse chromosomes 2 and 4. Arthritis Research Conference 2005

57. Chesler EJ, Lu L, Wang JT, Langston MA, Manly KF, Williams RW: Genetic analysis of gene transcription in genetic reference populations and relations to complex phenotypes. 2005 Cold Spring Harbor laboratory meeting on systems biology: Global regulation of gene expression, Cold Spring Harbor, NY, USA, March 17 - 20, 2005

58. Chesler EJ, Lu L, Wang JT, Manly KF, Williams RW: WebQTL: An Internet resource for the integrative genetic analysis of gene expression and pain related phenotypes. The 24 annual scientific meeting of American pain society, Boston, MA, USA, March 30 – April 2, 2005

59. Dong H, Martin M, Colvin J, Ali Z, Wang L, Lu L, Williams RW, Rosen GD, John G. Csernansky JG, Cheverud J: Four Quantitative Trait Loci for Thalamic Volume in BXD Recombinant Inbred Mice. 2005 International Conference of Schizophrenia Research, Savannah, GA, USA April 2 to 6, 2005

60. Martin M, Dong H, Vallera D, Meltzer M, Lu L, Williams RW, Rosen GD, John G. Csernansky JG, Cheverud J: Quantitative Trait Loci for Ventral Hippocampal Volume in BXD Recombinant Inbred Mice. International Conference of Schizophrenia Research, Savannah, GA, USA April 2 to 6, 2005

61. Peirce JL, Bennett B, Chesler EJ, Williams RW Lu L: Genetic analysis of ethanol-related traits and gene expression in the LXS hippocampus. . The 35^th Neuroscience Meeting, Washington DC, USA, November 12-16, 2005

62. Chesler EJ, Scharff JA, Pitts SM, Lu L, Wang J, Manly KF, Langston MA, Williams RW: Systems genetics of central nervous system from genes to phenotypes. The 35^th Neuroscience Meeting, Washington DC, USA, November 12-16, 2005

63. Dong H, Martin M, Colvin J, Ali Z, Wang L, Lu L, Williams RW, Rosen GD, John G. Csernansky JG, Cheverud J: Volumes in BXD Recombinant Inbred Mice: Implications for Schizophrenia. The 35^th Neuroscience Meeting, Washington DC, USA, November 12-16, 2005

64. Martin M, Dong H, Vallera D, Meltzer M, Lu L, Williams RW, Rosen GD, John G. Csernansky JG, Cheverud J: Independent Quantitative Trait Loci Influence Ventral and Dorsal Hippocampal Volume in Recombinant, Inbred Strains of Mice. The 35^th Neuroscience Meeting, Washington DC, USA, November 12-16, 2005

65. Williams RW, Peirce JL, Wang J, Manly KF, Chesler EL, Cui Y, Lu L: Systematic Genetics of gene expression and the use of reference populations to integrate across biological scales. 2006 Cold Spring Harbor laboratory meeting on systems biology: Global regulation of gene expression, Cold Spring Harbor, NY, USA, March 23 - 26, 2006

66. Williams RW, Haik BG, Jiao Y, Gu W, Lu L, Geisert EE: A Systematic Genetic Approach to Define Expression Networks in Eye and Their Relations to Structure and Function. The ARVO 2006 Annual Meeting, Ft Lauderdale, Florida, USA, April 30 - May 4, 2006.

67. Kempermann G, Overall R, Peirce JL, Lu L, Goldowitz D, Gage FH, Goodwin S, Smit G, Airey D, Rosen G, Schalkwyk L, Sutter T, Nowakowski R, Watley S, Williams RW: Hippocampal Gene Networks in BXD Mice. The 5th Annual Complex Trait Consortium (CTC) Meeting, Chapel Hill, North Carolina, May 6-10, 2006

68. Peirce JL, Li H, Wang J, Manly KF, Hitzemann RJ, Belknap JK, Rosen GD, Sutter T, Goodwin S, Williams RW, Lu L: How replicable are mRNA expression QTLs? The 5th Annual Complex Trait Consortium (CTC) Meeting, Chapel Hill, North Carolina, May 6-10, 2006

69. Boughter JD Jr, Baird JP, St. John SJ, Williams RW, Lu L, Heck D: Genetic basis of Lick Rate and Lick Microstructure in Mice. The 8^th Annual Meeting Of IBANGS, Vancouver, Canada, May 19-22, 2006

70. Yang RJ,Mozhui K, Lu L, Williams RW, Holmes A: Identifying genetic factors controlling amygdala morphology and emotion-related phenotypes in BXD recombinant inbred mice. IBNS 15th Annual Meeting, Whistler, Canada, May 23-28, 2006

71. Peirce JL, Putman HA, Miles MF, Parker CC, Bennett B, Li H, Wang J, Manly KF, Hitzemann RJ, Belknap JK, Rosen GD, Chesler EJ, Williams RW, Lu L: Genetic association of gene expression with alcohol phenotypes. The 29^thAnnual Scientific Meeting of the  Research Society on Alcoholism, Marriott Waterfront Hotel, Baltimore, Maryland, June 23-29, 2006

72. Jan TA, Reiner DJ, Peirce JL, Li CX, Boughter JD, Lu L, Williams RW, Waters RS: Genetic analysis of tongue size and tongue weight in recombinant inbred strains of mice. Am Chem Senses 28, 2006

73. Peirce J, Goldowitz D, Williams RW, Lu L, Mozhui K, Goodwin S, Sutter TR, Rosen GD, Overall RW, Kempermann GT, Gage FH, Smit AB, Airey DC, Schalkwyk LC, Nowakowski RS, Hayes NL: Genetic dissection of structural variation in the BXD hippocampus: New mapping and microarray-derived candidate genes for the Hipp1a locus. The 36^th Neuroscience Meeting, Atlanta, USA, October 14-18, 2006

74. Kempermann GT, OverallRW, PeirceJ, Lu L, GoldowitzD, GageFH, GoodwinS, SmitG, AireyDC, RosenGD, SchalkwykLC, SutterTR, NowakowskiRS, HayesNL, Whatley S, Williams RW: Neurogenesis-related hippocampal gene networks from the BXD recombinant inbred mouse panel using a genetical genomics approach. The 36^th Neuroscience Meeting, Atlanta, USA, October 14-18, 2006

75. Mozhui K, Hamre KM, Lu L, Williams RW: Complex Trait Analysis and Genetic Covariance of the Morphology of Basolateral Amygdala Complex in Recombinant Inbred Mice. The 36^th Neuroscience Meeting, Atlanta, USA, October 14-18, 2006

76. Mozhui K, Lu L, Williams RW: A Network of Co-Regulated Trans-Genes With Common Linkage to Distal Chromosome. The 20^th International Mouse Genome Conference, Charleston, South Carolina, USA, November 12-15, 2006.

77. Lu L and members of the Hippocampus Consortium: Genetic dissection of transcriptional regulatory network in mouse hippocampus. The 20^th International Mouse Genome Conference, Charleston, South Carolina, USA, November 12-15, 2006.

78. MountzJD, Lu L, YiN, BanerjeeS, WilliamsRW, Hsu HC: Multiplex inheritance of generalized autoimmune disease in BXD2 recombinant inbred strain of mice. The 70th annual meeting of the American College of Rheumatology, Washington DC, November 10-15, 2006

79. Marshall D, Peirce J, Zhou F, Lu L, Manly K, Williams RW, Stuart J: QTL Mapping in CXB mice: a mouse model for rheumatoid. UT-ORNL-KBRIN Bioinformatics summit 2007, at Paris Landing State Park, Buchanan, TN on April 13-15, 2007.

80. Abdeltawab N, Aziz RK, Kansal R, Lu L, Williams RW, Kotb M: Bioinformatics mapping of genetic loci modulating susceptibility to severe streptococcal sepsis using a reference population of recombinant inbred mice. UT-ORNL-KBRIN Bioinformatics summit 2007, at Paris Landing State Park, Buchanan, TN on April 13-15, 2007.

81. Yan J, Jiao Y, Lu L, Williams RW, Gu W: Effects of vitamin C on optimal liver health in mice: a microarray analysis of sfx mice deficient for Gulo. UT-ORNL-KBRIN Bioinformatics summit 2007, at Paris Landing State Park, Buchanan, TN on April 13-15, 2007.

82. Parker CC, Larson CJ, Carosone-Link P, Lu L, Bennett B: Genetics of basal plasma corticosterone levels in the LXS recombinant inbred mouse strains. International Behavioural and Neural Genetics Society Annual Meeting, at Doorwerth, The Netherlands on May 21-25, 2007.

83. Osadchuk AV, Djakov MS, Baburov YuV, Airey DC, Lu L, Threadgill DW, Williams RW: Multiple-QTL approach with epistatic interactions to genetic dissection of quantitative complex traits in the composite experimental design consisting of extended RIX cross and F2 generation of their progenitor strains. The 6th Annual Complex Trait Consortium (CTC) Meeting, Braunschweig, Germany, May 26-29, 2007

84. Ciobanu DC, Lu L, Sun Z, Williams RW: Validation of strong cis - effects in genetic studies of gene expression: what's real, what's not. The 6th Annual Complex Trait Consortium (CTC) Meeting, Braunschweig, Germany, May 26-29, 2007

85. Lu L, Bennett B, Mozhui K, Ciobanu DC, Williams RW: Expression genetic analysis of the hippocampus of 75 LXS RI strains using the Illumina Mouse-6 array platform. The 6th Annual Complex Trait Consortium (CTC) Meeting, Braunschweig, Germany, May 26-29, 2007

86. Cook MN, Li HZ, Bennett B, Putman AH, Williams RW, and Lu L: Ethanol mediation of stress response in LXS RI mice: Behavioral and QTL findings. The 30^thAnnual Scientific Meeting of the  Research Society on Alcoholism, Chicago, Illinois, USA, July 7-12, 2007

87. Lu L, Cook MN, Bennett B, Williams RW: Genetic dissection of transcriptional regulatory network in the hippocampus of LXS mice. . The 30^thAnnual Scientific Meeting of the  Research Society on Alcoholism (RSA), Chicago, Illinois, USA, July 7-12, 2007

88. Boughter JD Jr, Bajpai T, St John SJ, Williams RW, Lu L, and Heck D: Genetic analysis of oromotor movements in inbred and BXD recombinant inbred mice. The 37^th Neuroscience Meeting, San Diego, California, USA, November 3-7, 2007

89. Rosen GD, Gaglani S, Pung CJ, Owens CB, Caplow J, Kim H, Lu L: Identification of QTLs for both neocortical and striatal volume on Chr 6 in the BXD recombinant inbred mouse. The 37^th Neuroscience Meeting, San Diego, California, USA, November 3-7, 2007

90. Geisert EE, Lu L, Gu W, Williams RW: Covariance of mRNA Identifies Genetic Networks in the Eye. The ARVO 2008 Annual Meeting, Ft Lauderdale, Florida, USA, April 27- May 1, 2008

91. Wang XS, Hori RT, Lu L, Williams RW: Reverse complex trait analysis of transcripts involved in CNS function. The 10th Annual Meeting of the International Behavioural and Neural Genetics Society (IBANGS), Portland, Oregon USA May 5-9, 2008

92. Boughter JD Jr, Bajpai T, St. John SJ, Williams RW, Lu L, and Heck DH: Genetic analysis of fluid licking in inbred and BXD recombinant inbred mice. The 10th Annual Meeting of the International Behavioural and Neural Genetics Society (IBANGS), Portland, Oregon USA May 5-9, 2008

93. Mozhui K, Ciobanu DC, Lu L, Williams RW: Dissection of a transcriptional control hotspot on mouse distal chromosome 1 that modulated neurobehavioral phenotypes. The 7th Annual Complex Trait Consortium (CTC) Meeting, Montreal, Canada, May 30- June3, 2008

94. Boon ACM, Williams RW, Lu L and Webby RJ: Survival after H5N1 virus infection; It's in your Genes. Third European Influenza Conference, Vilamoura Portugal, 14-17 September 2008.

95. Geisert EE,Lu L,Williams RW,Orr WE, Templeton JP, Freeman-Anderson NE: Covariance of Gene Expression and Gene Networks in the Mouse Retina. The ARVO 2009 Annual Meeting, Ft Lauderdale, Florida, USA, May 3 - 7, 2009.

96. Whitney IE, Raven MA, Lu L, Williams RW, Reese BE: A QTL on Chromosome 10 Modulates Cone Photoreceptor Number in the Mouse Retina. The ARVO 2009 Annual Meeting, Ft Lauderdale, Florida, USA, May 3 - 7, 2009.

97. Lu L, Wang X, Williams RW: Genetic regulation of the expression of GABA-A receptors in mouse brain. The 11th Annual Meeting of the International Behavioural and Neural Genetics Society (IBANGS), Dresden, Germany, June 4-9, 2009

98. Wang, X, Chen Y, Lu L: Preliminary study of expression QTL analysis of candidate genes related to Alzheimer's disease. The 39^th Neuroscience Meeting, Chicago, Illinois, USA, October 17-21, 2009

99. Porcu P, O'Buckley TK, Song SC, Chesler EJ, Lu L, Williams RW and Morrow AL: Dexamethasone suppression of deoxycorticosterone across the BXD recombinant inbred mice: a putative neuroactive steroid biomarker for alcohol and anxiety phenotypes. The 39th Neuroscience Meeting, Chicago, Illinois, USA, October 17-21, 2009

100. Wang X, Chen Y, Lu L: Preliminary study of expression QTL analysis of candidate genes related to Alzheimer's disease. The 39th Neuroscience Meeting, Chicago, Illinois, USA, October 17-21, 2009

101. Whitney IE, Taylor K, Miller H, Lu L, Reese BE and Williams RW: Identifying novel disease candidate genes using microarray expression analysis of recombinant inbred mice. The 23^rd international mammalian genome conference (IMGC), La Jolla, California, November 1-4, 2009

102. Mulligan MK, Wang X, Lu L, Williams RW: GENETIC REGULATION OF THE EXPRESSION OF MAJOR GABA-A RECEPTOR SUBUNITS IN MOUSE BRAIN. The 23rd international mammalian genome conference (IMGC), La Jolla, California, November 1-4, 2009

103. Williams RW, Wang X, Ciobanu D, Cui Y, Li Z, Mozhui K, Mulligan M, Nelson S, Taylor W, Thomason D, Williams EG, Lu L: Next-Generation Genomic Resources for the BXD Genetic Reference Panel. The BXD world international meeting on BXD phenotyping. Braunschweig, Germany, November 30 - December 1, 2009

104. Miyairi I, Lu L, Williams RW and Byrne GI: Genetic susceptibility to acute and chronic Chlamydia infection. The BXD world international meeting on BXD phenotyping. Braunschweig, Germany, November 30 - December 1, 2009

105. Mulligan MK, Li Z, Wang X, Miles MF, Lu L, Williams RW: Functional insertion of a B2 SINE in Comt controls 3' UTR length and generates widespread expression and behavioral differences among inbred strains of mice. The 12th Annual Meeting of the International Behavioural and Neural Genetics Society (IBANGS), Halifax, Nova Scotia, Canada, May 12-16, 2010

106. Wang X, Agarwala R, Capra T, Church DM, Ciobanu DC, Li D, Lu L, Mozhui K, Mulligan MK, Nelson SF, Pollard KS, Taylor WL, Thomason DB, Williams RW: A whole genome sequence for DBA/2J and its use in reverse complex trait analysis. The 12th Annual Meeting of the International Behavioural and Neural Genetics Society (IBANGS), Halifax, Nova Scotia, Canada, May 12-16, 2010

107. Reinius B, Kullander K, Rosen GD, Lu L, Williams RW, and Jazin E: Regional differences in sexually dimorphic gene expression in adult mice brain. The 12th Annual Meeting of the International Behavioural and Neural Genetics Society (IBANGS), Halifax, Nova Scotia, Canada, May 12-16, 2010

108. Glenn D. Rosen GD, and Lu L: Genetic networks modulating neocortical neuronal migration disorders in BXD recombinant inbred lines. The 9th Annual Complex Trait Consortium (CTC) Meeting, Chicago, USA, May 8-10, 2010

109. Wang X, Agarwala R, Capra T, Chen Z, Church DM, Ciobanu DC, David Li1, Lu L, Mozhui K, Mulligan MK, Nelson SF, Katherine S Pollard KS, Taylor WL, Thomason DB, Williams RW: High-throughput sequencing of the DBA/2J mouse genome. The 9th Annual Complex Trait Consortium (CTC) Meeting, Chicago, USA, May 8-10, 2010

110. Mozhui K, Wang X, Mulligan MK, Lu L, Williams RW: Exon-Level Analysis of Synaptic Gene Expression: A Neurexin 1 Network in the Hippocampus. The 9th Annual Complex Trait Consortium (CTC) Meeting, Chicago, USA, May 8-10, 2010

111. Cui X, Cook M, Li Z, Hamre K and Lu L: Genetic and Stress Influence on DNA Methylation in Mouse Hippocampus. The 9th Annual Complex Trait Consortium (CTC) Meeting, Chicago, USA, May 8-10, 2010

112. Overall R, Lu L, Williams RW and Kempermann G: Transcriptional co-expression networks in the mouse hippocampus: application to adult neurogenesis phenotypes. The 9th Annual Complex Trait Consortium (CTC) Meeting, Chicago, USA, May 8-10, 2010

113. Jablonski MM, Lu H, Pullen M, Wang X, Lu L, Williams RW: Genetic dissection of the Gpnmb network in the eye. The ARVO 2010 Annual Meeting, Ft Lauderdale, Florida, USA, May 2 - 6, 2010.

114. Chen H, Guan H, Lu H, Jablonski MM, Williams RW, Lu L: Genetic dissection of IOP regulation. The ARVO 2010 Annual Meeting, Ft Lauderdale, Florida, USA, May 2 - 6, 2010.

115. Lu H, Guan H, Lu L, Williams RW, Jablonski MM: Genetic Dissection Of Iris Transillumination Defects And Pigmentary Dispersion Syndrome. The ARVO 2010 Annual Meeting, Ft Lauderdale, Florida, USA, May 2 - 6, 2010.

116. Geisert EE, Lu L, Williams RW, Orr WE, Abner CW, Templeton JP, Freeman-Anderson NE: Gene Networks in the Mouse Retina. The ARVO 2010 Annual Meeting, Ft Lauderdale, Florida, USA, May 2 - 6, 2010.

117. Lu L, Wang X, Williams RW, Cook M: Genetic analysis of anxiety-related behavior and gene expression in BXD strains. The 40th annual Behavior Genetics Association (BGA) meeting, Seoul, South Korea, June 2-5, 2010

118. Porcu P, O'Buckley TK, Song SC, Chesler EJ, Lu L, Williams RW, Miles MF and Morrow AL: Identification of QTLs for deoxycorticosterone levels across the BXD RI mice: a putative neuroactive steroid biomarker for alcohol phenotypes. The 33rd Annual Scientific Meetings of the Research Society on Alcoholism (RSA), San Antonio, Texas, USA, June 26-30, 2010

119. Hamre K, Cui X, Li Z, Hori R, Williams RW, Lu L: Strain-specific stress-induced modification of gene expression: Is DNA methylation involved? The 33rd Annual Scientific Meetings of the Research Society on Alcoholism (RSA), San Antonio, Texas, USA, June 26-30, 2010

120. Han X, Chen Y, Ciobanu DC, Lu L, Wang X: Genetic dissection of the variation expression of Gsto1 in mouse hippocampus. Alzheimer's Association International Conference on Alzheimer's Disease 2010 (AAICAD), Honolulu, Hawaii, USA, July 10-15, 2010

121. Williams RW, Yan L, Zhou X, Lu L, Centeno A, Kuan L, Hawrylycz M, Rosen GD: Global Exploratory Analysis of Massive Neuroimaging Collections using Microsoft Live Labs Pivot and Silverlight. The Third International Congress  on Mathematical Software (ICMS), Kobe, Japan, September 13-17, 2010

122. Uhlmann RA, Taylor ML, Williams RW, Mari G and Lu L: Quantitative Trait Loci Controlling Uterine Weight in Mus musculus. Society for Gynecologic investigation (SGI) 58th Annual Scientific Meeting, Miami Beach, Florida, USA, March 16-19, 2011

123. Taylor ML, Uhlmann RA, Williams RW, Lu L, Mari G: Quantitative Trait Loci Controlling Ovarian Weight in Mus musculus. Society for Gynecologic investigation (SGI) 58th Annual Scientific Meeting, Miami Beach, Florida, USA, March 16-19, 2011

124. Uhlmann RA, Taylor ML, Mari G, Lu L and Williams RW: Quantitative Trait Loci Controlling Uterine Horn Length in Mus musculus. Society for Gynecologic investigation (SGI) 58th Annual Scientific Meeting, Miami Beach, Florida, USA, March 16-19, 2011

125. Taylor ML, Uhlmann RA, Williams RW, Lu L, Mari G: Quantitative Trait Loci Controlling Uterine Body Length and Width in Mus musculus. Society for Gynecologic investigation (SGI) 58th Annual Scientific Meeting, Miami Beach, Florida, USA, March 16-19, 2011

126. Block A, Watson ER, Geisert EE, Lu L, Williams RW, Jablonski MM: Analysis of the Tyrp1 Gene Network in the Eye. The ARVO 2011 Annual Meeting, Ft Lauderdale, Florida, USA, May 1-5, 2011.

127. Geisert EE, Abner CW, Lu L, Williams RW, Orr WE, Templeton JP, Freeman NE: Genetic Networks Activated by Optic Nerve Injury. The ARVO 2011 Annual Meeting, Ft Lauderdale, Florida, USA, May 1-5, 2011.

128. Mulligan MK, Wang X, Ingels J, Mozhui K, Lu L, and Williams RW: A recent mutation in the C57BL/6J genome results in decreased levels of Gabra2 and has a downstream effect on gene expression and behavior. The 13th Annual Meeting of the International Behavioural and Neural Genetics Society (IBANGS), Rome, Italy, May 11-14, 2011

129. Lu L, Mulliga M, Chen Y, Ciobanu D, Wang X, and Williams RW: Discovering new Alzheimer disease related genes and gene networks through systems biology methods. The 2nd Annual World Congress of NeuroTalk, Dalian, China, May 22-25, 2011

130. Boughter J, Lu L: Identifying Mechanisms Controlling Brain Stem Pattern Generators Using Genetic Analysis. The 2nd Annual World Congress of NeuroTalk, Dalian, China, May 22-25, 2011

131. Wang X, Mulligan MK, Mozhui K, Lu L, Chen Z, Nelson SF, Taylor WL, and Williams RW: Comparison of variant detections using whole genome sequencing of the DBA/2J mouse strain. The 10th Annual Complex Trait Consortium (CTC) Meeting, Washington DC, USA, June 22-25, 2011.

132. Zhu J, Zhu Z, Zhang C, Wang X, Lu L, Williams RW: A combined method of mapping QTL, QTN and QTT for complex traits. The 10th Annual Complex Trait Consortium (CTC) Meeting, Washington DC, USA, June 22-25, 2011.

133. Kambhampati SK, Jones BC, Sutti S, Cavigelli SM., Ragan C, Morméde P, Williams RW and Lu L: chronic mild stress and drinking in the dark: a new model to study the effects of genes and environment on alcohol consumption. Mouse Genetics 2011 meeting, Washington DC, USA, June 22-25, 2011

134. Jones BC, Jellen LC, Unger EL, Earley CJ, Lu L, Williams RW and Wang X: iron deficiency up-regulates dopamine-related genes in the ventral midbrain in inbred mice. Mouse Genetics 2011 meeting, Washington DC, USA, June 22-25, 2011

135. Rooney RJ, Patel D, Lu L, Williams RW, Hamre KM: Analysis of the role of gender and genetics in of the response of the liver to acute ethanol exposure using BXD recombinant inbred mice. The 34th Annual Scientific Meetings of Research Society on Alcoholism (RSA), Atlanta, Georgia, USA, June 25-29, 2011

136. Porcu P, O'Buckley TK, Gupta SS, Lu L, Williams RW and Morrow AL: Genetic differences in the effects of ethanol on brain 3a,5a-thp levels across selected bxd recombinant inbred mouse strains. The 34th Annual Scientific Meetings of Research Society on Alcoholism (RSA), Atlanta, Georgia, USA, June 25-29, 2011

137. Lu L, Wang X, Williams RW, Hamre KM: Genetic analysis of the microRNA processing genes, Drosha and Dicer, and their roles in ethanol- and stress-related phenotypes. The 34th Annual Scientific Meetings of Research Society on Alcoholism (RSA), Atlanta, Georgia, USA, June 25-29, 2011

138. Liu Y, Wang X, Mulligan M, Williams RW, Lu L: Expression QTL and regulatory network analysis of Bleomycin hydrolase gene. Alzheimer's Association International Conference on Alzheimer's Disease 2011 (AAICAD), Paris, France, July 16-21, 2011

139. Toutounchian JJ, Thompson KE, Tigyi GJ, Williams RW, Lu L, Yates CR: Heritability of Radiation-Induced Injury in BXD Recombinant Inbred Strains: The Genetics of Hematopoietic-Acute Radiation Syndrome. The 14th International Congress of Radiation Research, Warsaw, Poland, August 28, 2011

140. Mozhui K, Lu L, Williams RW: Systems Genetics of the Basolateral Amygdala: Relating the Transcriptome to Ontogeny, Structure and Function. XIXth World Congress of Psychiatric Genetics, Washington, DC, September 10-14, 2011

141. Yin L, Lu L, Jones BC: Dopamine, oxygen and iron homeostasis might be involved in paraquat neurotoxicity in mice. The 41th Neuroscience Meeting, Washington DC, USA, November 12-16, 2011

142. Abdeltawab NF, Lu L, Williams RW, Kotb M: Meta-analysis of genes within QTLs of group A streptococcal sepsis and their expression QTLs reveal pathways modulating host differential response to streptococcal sepsis. UT-ORNL-KBRIN Bioinformatics Summit 2012, Louisville, KY, USA, March 30 - April 1, 2012

143. Swaminathan S, Lu H, Williams RW, Lu L, Jablonski MM: Genetic Factors Affecting Iris Transillumination Defects In Recombinant Inbred Strains Of Mice: Correlation Analysis, Mapping And Mathematical Modeling. The ARVO 2012 Annual Meeting, Fort Lauderdale, Florida, USA, May 6-10, 2012.

144. Grzyb AN, Overall R, Fabel KS, Silhavy J, Lu L, Williams RW, Pravenec M, and Kempermann G: Genetic regulation of adult hippocampal neurogenesis in HXB/BXH recombinant inbred rats, a model of metabolic syndrome. The 11th Annual Complex Trait Consortium (CTC) Meeting, Paris, France, June 12-15, 2012

145. Skobowiat C, Nejati R, Lu L, Williams RW, and Slominski A: Ultraviolet radiation modulates cutaneous hypothalamic–pituitary–adrenal (HPA) axis in C57BL/6J and DBA/2J strains with divergent disease susceptibility. Pan American Society for Pigment Cell Research (PASPCR) 2012, Park City, UT, September 19-22, 2012, Pigment cell & melanoma Vol. 25 No 5 Sept. 2012 pp690-691

146. Williams RW, Jablonski MM, Geisert EE, Lu L: Systems Genetics of Molecular Networks: The Glaucoma-Pigmentation Link. Pan American Society for Pigment Cell Research (PASPCR) 2012, Park City, UT, September 19-22, 2012, Pigment cell & melanoma Vol. 25 No 5 Sept. 2012 pp690-691

147. DuBose CS, Mulligan M, Williams RW, Lu L, Hamre KM: Analysis of the role of microRNAs in genetic differences in phenotypic responses to drugs of abuse and alcohol as assessed through bioinformatic correlations with expression of Dicer, Drosha and Pasha. The 42th Neuroscience Meeting (SFN), New Orleans, LA, USA, October 13~17, 2012

148. Chen Y, Mulligan M, Wang XD Lu L: Genetic dissection of the variation in expressionof glutathione S-transferasein BXD mice. Neurodegeneration Conference 2012, Xcaret, Mexico, November 27 – December 1, 2012

149. Jones BC, Unger EL, Alam G, Yin L, Lu L, Williams RW, Miller DB, O'Callaghan JP: IRON: KEY TO INDIVIDUAL DIFFERENCES IN SUSCEPTIBILITY TO PESTICIDE NEUROTOXICITY? Fifth Meeting of the International BioIron Society, University College London UK, April 14 – 18, 2013

150. Jablonski MM, Swaminathan S, Lu H, Wiggs JL, Williams RW, Lu L,: Systems Genetics of Intraocular Pressure—Mice to Humans: The Use of BXD Murine Reference Panel for Identifying Novel Genetic Modulators of Glaucoma and Bidirectional Translation. The ARVO 2013 Annual Meeting, Seattle, Washington, USA, May 5-9, 2013.

151. Roy S, Scattoni ML,Lu L, Williams RW: Genetic and parametric analysis of infant vocalization between C57BL/6J, DBA/2J, and reciprocal F1 hybrids. The 43th Neuroscience Meeting (SFN), San Diego, CA, USA, November 9~13, 2013

152. Hamre KM, Pandey A, Mulligan M, Ingels J, Yue J, LU L: Strain differences in expression of microRNA in the hippocampus assessed using next generation sequencing technology: comparison of DBA/2J and C57BL/6J mouse strains. The 43th Neuroscience Meeting (SFN), San Diego, CA, USA, November 9~13, 2013

153. Crusio WE, Algeo MP, Bonheur B, Lu L, Williams RW, Delprato A; Genetic dissection of variation in hippocampal structure and learning in the expanded family of BXD mouse strains. The 43th Neuroscience Meeting (SFN), San Diego, CA, USA, November 9~13, 2013Alam G, Miller D, O'Callaghan JP, Lu L, Williams,RW, Jones BC: Variability in toxicity: who is susceptible and why? The 53th annual meeting of Society of Toxicology (SOT), Phoenix, Arizona, USA, March 23-27, 2014

154. Huang Y, Wang L, Liu X, Yan J, Williams RW, Lu L, Jiao Y, Gu W: Genome wide analysis of sex difference ingene expression profiles of bone formations. UT-ORNL-KBRIN Bioinformatics Summit 2014, Cadiz, KY, USA, April 11-13, 2014

155. Zhao W, Lu L, Williams RW, Chen Y, Meng W, Sun Y: Genetic control of heart weight in mouse and man. UT-ORNL-KBRIN Bioinformatics Summit 2014, Cadiz, KY, USA, April 11-13, 2014

156. Wenyuan Zhao, Lu Lu, Robert Williams, Yuanjian Chen, Weixin Meng, Yao Sun: Genetic control of heart weight in mouse and man. Experimental Biology meeting (EB) 2014, San Diego, CA, USA, April 26~30, 2014

157. Shankar Swaminathan, Hong Lu, Janey L. Wiggs, Robert W. Williams, Lu Lu, Monica M. Jablonski: Dissection of a QTL Locus on Mouse Proximal Chromosome 5 that Modulates Intraocular Pressure (IOP) leads to Identification of a Potential New Drug Target for Glaucoma. The ARVO 2014 Annual Meeting, Orlando, Florida, USA, May 4-8, 2014.

158. Megan Mulligan, Pandey A, Roy S, Ingels J, Lu L, Williams RW: Leveraging a reduced complexity cross between C57BL/6J Substrains: Reduced genetic complexity facilitates candidate gene discovery. The 16th Annual Meeting of the International Behavioural and Neural Genetics Society (IBANGS), Chicago, Illonois, USA, May 10-13, 2014

159. Hamre KM, Mulligan M, Ingels J, Yue J, Lu L: Identification of a network of microRNAs that have a significant role in hippocampal morphology and hippocampal-related behaviors. The 16th Annual Meeting of the International Behavioural and Neural Genetics Society (IBANGS), Chicago, Illonois, USA, May 10-13, 2014

160. Delprato A, Algéo MP, Bonheur B, Lu L, Williams RW, Crusio WE: The genetic architecture of the hippocampus and spatial learning. The 16th Annual Meeting of the International Behavioural and Neural Genetics Society (IBANGS), Chicago, Illonois, USA, May 10-13, 2014

161. Wang X, Pandey A, Mulligan MK, Capra JA, Chen Z, Ciobanu DC, Jouline IB, Nelson SF, Pollard KS, Taylor WL,Lu L, Williams RW: A start at Phenome-Wide Association Using the Expanded Family of BXD Strains. The 13th Annual Complex Trait Consortium (CTC) Meeting, Berlin, Germany, May19-22, 2014

162. Grzyb AN, Rupert W. Overall RW, Silhavy J, Fabel KS, Lu L, Stuchlik A, Robert W. Williams RW, Pravenec M, and Gerd Kempermann GK: Genetic regulation of adult hippocampal neurogenesis in HXB/BXH recombinant inbred rats, a model of metabolic syndrome. The 5th International Congress on Stem Cells and Tissue Formation. Dresden, Germany, July 8-11, 2014

163. Lu Lu, Robert W. Williams, Megan Mulligan, Kristin Hamre: MicroRNAs and other non-coding RNAs and their involvement in genetic differences in stress- and ethanol-related phenotypes: Bioinformatic analyses using BXD mice. The 37th Annual Scientific Meetings of Research Society on Alcoholism (RSA), Bellevue, Washington, USA, June 21-25, 2014

164. Williams RW, Mulligan MK, Pandey A, Wang X, Lu L: phenome-wide association: new opportunities and new problems. The 37th Annual Scientific Meetings of Research Society on Alcoholism (RSA), Bellevue, Washington, USA, June 21-25, 2014

165. Crusio W, Bonheur B, Algeo MP, Lu L, Williams RW, Delprato A: Systems genetics analysis of spatial learning and hippocampal neuroanatomical variation in mice. The 9^th FENS (Federation of European Neuroscience Societies) forum of Neuroscience, Milan, Italy, July 5-9, 2014

166. Hamre KM, Lattimer S, Ingels J, Lu L: Strain-specific differences in microrna expression in the hippocampus following exposure to stress and/or alcohol. The 44th Neuroscience Meeting (SFN), Washington DC, USA, November 15~19, 2014

167. Snigdha Roy, Maria Luisa Scattoni, Detlef H. Heck, Lu Lu, Robert W. Williams: Genetic dissection of infant vocalizations. The 44th Neuroscience Meeting (SFN), Washington DC, USA, November 15~19, 2014

168. Gelareh Alam, Diane Miller, James O'Callaghan, Lu Lu, Robert Williams, Byron Jones: Systems genetics analysis of mptp neurotoxicity. The 54th Annual Meeting of the Society of Toxicology (SOT), San Diego, California, March 22~26, 2015

169. Hua Geng, Heng-Fu Bu, Karl Pfeifer, Longtao Wu, Ashutosh Pandey, Fangyi Liu, Peng Wang, Xiao Wang, Suhail Akhtar, Lu Lu, Jindan Yu, and Xiao-Di Tan: H19 is an early response long non-coding RNA (LncRNA) and controls the homeostasis of c-Fos gene expression in intestinal inflammation. Digestive Disease Week (DDW) 2015, Washington DC, May 17~19, 2015

170. Anna N. Grzyb, Rupert W. Overall, Jan Silhavy, Zeina Nicola, Josephine Boehme, Ruslan Rust2, Klaus S. Fabel, Karel Vales, Lu Lu, Ales Stuchlik3, Robert W. Williams, Michal Pravenec, and Gerd Kempermann: Crosstalk between neurogenesis and physiology: genetic and transcriptional networks in HXB/BXH recombinant inbred rats, a model of metabolic syndrome. Adult Neurogenesis Conference in Dresden Germany on May 5-8, 2015

171. Guannan Zhao, Jinggang Yin, Qingqing Gu, Lu Lu, Edward Chaum, Junming Yue: Lentiviral CRISPR/Cas9 mediated genome editing reveals functional difference of Notch receptors 14TH ANNUAL UT-KBRIN Bioinformatics Summit 2015, Buchanan, TN, USA, March 20-22, 2015